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Details

Stereochemistry ACHIRAL
Molecular Formula C14H15N5O3
Molecular Weight 301.3006
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TROQUIDAZOLE

SMILES

[O-][N+](=O)C1=CN=C2C=CC=CC2=C1NC(=N)N3CCOCC3

InChI

InChIKey=UUJSXEHRMRPYEX-UHFFFAOYSA-N
InChI=1S/C14H15N5O3/c15-14(18-5-7-22-8-6-18)17-13-10-3-1-2-4-11(10)16-9-12(13)19(20)21/h1-4,9H,5-8H2,(H2,15,16,17)

HIDE SMILES / InChI

Molecular Formula C14H15N5O3
Molecular Weight 301.3006
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Troquidazole (EGIS-4136) is a radiosensitizer. It is a nitroquinoline derivative which enhances the radiosensitivity of hamster’s ovarian cells in both normoxia and hypoxia. Misonidazole at a concentration of 5 mM exerted a radiosensitizing effect as strong as 0.5 mM EGIS-4136.

Approval Year

PubMed

Sample Use Guides

In Vivo Use Guide
Rats: single oral dose of 50 mg/kg
Route of Administration: Oral
Substance Class Chemical
Record UNII
41X4FOR202
Record Status Validated (UNII)
Record Version