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Development Status

Investigational

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Primary Target

Peroxisome proliferator-activated receptor gamma

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Phase I

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Unknown

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Condition

Diabetes mellitus

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Primary

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Pfizer

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DARGLITAZONE

AVP9C03Z3K

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Status:

Investigational

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

Peroxisome proliferator-activated receptor gamma

Conditions:

Diabetes mellitus

Darglitazone is a member of the thiazolidinedione class of drugs and an agonist of peroxisome proliferator-activated receptor-γ (PPAR-γ), an orphan member of the nuclear receptor superfamily of transcription factors. It has a variety of insulin-sensi...

tizing effects, such as improving glycemic and lipidemic control, and is used in the treatment of metabolic disorders such as type II diabetes. Darglitazone sodium had been in phase I clinical trials by Pfizer for the treatment of type 2 diabetes. However, this study has been discontinued.

DARGLITAZONE SODIUM

A1P35HS4XI

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Search for Structure

Status:

Investigational

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

Peroxisome proliferator-activated receptor gamma

Conditions:

Diabetes mellitus

Darglitazone is a member of the thiazolidinedione class of drugs and an agonist of peroxisome proliferator-activated receptor-γ (PPAR-γ), an orphan member of the nuclear receptor superfamily of transcription factors. It has a variety of insulin-sensi...

tizing effects, such as improving glycemic and lipidemic control, and is used in the treatment of metabolic disorders such as type II diabetes. Darglitazone sodium had been in phase I clinical trials by Pfizer for the treatment of type 2 diabetes. However, this study has been discontinued.

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