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Showing 1 - 3 of 3 results

Status:
US Approved Rx (1991)
First approved in 1991

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pentostatin, also known as 2’-deoxycoformycin (DCF) under the trade name Nipent, is a potent inhibitor of the enzyme adenosine deaminase and is isolated from fermentation cultures of Streptomyces antibioticus. It was developed by Parke-Davis (now Pfi...
Status:
US Approved Rx (2023)
First approved in 1959

Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:


N,N’N’-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. It is a stable derivative of N,N’,N’’- triethylenephosphoramide (TEPA). The radiomimetic action of thiotep...