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Showing 1 - 8 of 8 results

Status:
US Approved Rx (2024)
First approved in 1983

Class (Stereo):
CHEMICAL (ABSOLUTE)



Cyclosporins are cyclic polypeptide macrolides that were originally derived from the soil fungus Tolypocladium inflatum. Cyclosporine (also known as cyclosporine A) was discovered by Sandoz and developed for the tretment of immune disorders. The drug...
Status:
US Approved Rx (1976)
First approved in 1976

Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:


Lomustine is used in the treatment of certain neoplastic diseases. Although it is generally agreed that lomustine alkylates DNA and RNA, it is not cross resistant with other alkylators. As with other nitrosoureas, it may also inhibit several key enzy...
Status:
US Approved Rx (1970)
First approved in 1970

Class (Stereo):
CHEMICAL (RACEMIC)



Mitotane is an oral chemotherapeutic agent indicated in the treatment of inoperable adrenal cortical carcinoma of both functional and nonfunctional types. Mitotane can best be described as an adrenal cytotoxic agent, although it can cause adrenal inh...
Status:
US Approved Rx (2019)
First approved in 1959

Class (Stereo):
CHEMICAL (MIXED)

Targets:


Cyclophosphamide (the generic name for Cytoxan, Neosar, Revimmune), also known as cytophosphane, is a nitrogen mustard alkylating agent, from the oxazophorines group. It is used to treat various types of cancer and some autoimmune disorders. It is a ...
Status:
US Approved Rx (1957)
First approved in 1957

Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:


Chlorambucil is a bifunctional 12 alkylating agent of the nitrogen mustard type that has been found active against selected human 13 neoplastic diseases. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, inducing DNA dam...
Status:
US Previously Marketed
First approved in 1970

Class (Stereo):
CHEMICAL (ABSOLUTE)

Targets:


Plicamycin (INN, also known as mithramycin; trade name Mithracin) is an antineoplastic antibiotic produced by Streptomyces plicatus. Plicamycin belongs to the group of medicines known as antineoplastics. It may be used to treat certain types of cance...
Status:
US Approved Rx (2019)
First approved in 1959

Class (Stereo):
CHEMICAL (RACEMIC)

Targets:


Cyclophosphamide (the generic name for Cytoxan, Neosar, Revimmune), also known as cytophosphane, is a nitrogen mustard alkylating agent, from the oxazophorines group. It is used to treat various types of cancer and some autoimmune disorders. It is a ...
Status:
US Approved Rx (2019)
First approved in 1959

Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:


Cyclophosphamide (the generic name for Cytoxan, Neosar, Revimmune), also known as cytophosphane, is a nitrogen mustard alkylating agent, from the oxazophorines group. It is used to treat various types of cancer and some autoimmune disorders. It is a ...