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4

Investigational

1

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Primary Target

Cytochrome b

1

Fusarium graminearum

1

ubiquinol-cytochrome-c reductase activity

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Approval Year

Unknown

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Condition

Malaria

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Obesity

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Unknown

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Primary

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Originator

Japan

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Syngenta

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Chemical

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CAS

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FDA UNII

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PUBCHEM

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ALANWOOD

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EPA CompTox

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Salts, Hydrates, Esters, etc.

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Showing 1 - 5 of 5 results

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PYRACLOSTROBIN

DJW8M9OX1H

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Status:

Investigational

Class (Stereo):

CHEMICAL (ACHIRAL)

AZOXYSTROBIN

NYH7Y08IPM

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

ubiquinol-cytochrome-c reductase activity

Conditions:

Azoxystrobin is the first of a new class of pesticidal compounds called ß-methoxyacrylates, which are derived from the naturally-occurring strobilurins. Azoxystrobin is a broad spectrum fungicide with activity against several diseases on many edible ...

crops and ornamental plants. Some diseases controlled or prevented are rice blast, rusts, downy mildew, powdery mildew, late blight, apple scab, and Septoria. Azoxystrobin is marketed by Syngenta as single AS products under several trade names, the major ones for crop protection being: Amistar, Abound, Priori, Quadris, Dynasty for seed treatments, and Heritage for turf. Azoxystrobin (AZOX), a Qo inhibitor of mitochondrial respiratory complex III, exerts whole-body beneficial effects on the regulation of glucose and lipid homeostasis in high-fat diet-fed mice. Chronic treatment with AZOX reduced body weight and significantly improved glucose tolerance and insulin sensitivity in high-fat diet-fed mice. AZOX treatment resulted in decreased triacylglycerol accumulation and down-regulated the expression of genes involved in liver lipogenesis. AZOX increased glucose uptake in L6 myotubes and 3T3-L1 adipocytes and inhibited de novo lipogenesis in HepG2 cells.

FLUOXASTROBIN, (Z)-

87YQY15C4N

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

THIOPHANATE-METHYL

K4N81R84L8

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Fusarium graminearum

Conditions:

Thiophanate methyl is an approved EU fungicide used widely to control fungal diseases on crops. It has a low aqueous solubility, low volatility and tends not to be persistent in soil or water systems. It has a low mammalian toxicity, however it is an...

irritant, a skin sensitiser and may also be mutagen. It is moderately toxic to most aquatic organisms and earthworms but less so to birds and honeybees.

FLUOXASTROBIN

XQ43WY091Y

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

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