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Status:
US Approved Rx (1991)
First approved in 1991

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pentostatin, also known as 2’-deoxycoformycin (DCF) under the trade name Nipent, is a potent inhibitor of the enzyme adenosine deaminase and is isolated from fermentation cultures of Streptomyces antibioticus. It was developed by Parke-Davis (now Pfi...
Status:
US Approved Rx (2017)
First approved in 1964

Class (Stereo):
CHEMICAL (ABSOLUTE)

Targets:


Dactinomycin (actinomycin D) was isolated from Streptomyces by Selman Waksman in 1940s. The antibiotic shows anti-cancer activity; it was approved by FDA for the treatment of different cancer conditions among which are Ewing's sarcoma, Wilm's tumor, ...