U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
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Showing 1 - 10 of 20 results

Status:
US Approved Rx (2024)
First approved in 1995

Class (Stereo):
CHEMICAL (ACHIRAL)



Mycophenolic acid (MPA) possesses antibacterial, antifungal, antiviral, immunosuppressive and anticancer properties. Mycophenolic acid (MPA) is a fungal metabolite that was initially discovered by Bartolomeo Gosio in 1893 as an antibiotic against ant...
Status:
US Approved Rx (2025)
First approved in 1994

Class (Stereo):
CHEMICAL (ABSOLUTE)



Tacrolimus, previously known as FK506, is the active ingredient in Prograf. Tacrolimus is a macrolide immunosuppressant produced by Streptomyces tsukubaensis. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506...
Status:
US Approved Rx (2020)
First approved in 1987

Class (Stereo):
CHEMICAL (ABSOLUTE)



Lisinopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE). Lisinopril is marketed under the brand name ZESTRIL. ZESTRIL is indicated for the treatment of hypertension. It may be used alone as initial therapy or concomitantl...
Status:
US Approved Rx (2014)
First approved in 1981

Class (Stereo):
CHEMICAL (ACHIRAL)



Nifedipine has been formulated as both a long- and short-acting 1,4-dihydropyridine calcium channel blocker. Nifedipine is sold under the brand names Adalat and Procardia among others. Nifedipine decreases arterial smooth muscle contractility and sub...
Status:
US Approved Rx (2013)
First approved in 1954

Class (Stereo):
CHEMICAL (RACEMIC)



Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Warfarin is marketed under the brand name Coumadin among others. Coumadin (crystalline warfarin sodium) is an anticoagulant which acts by inhibiting...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)

Norleucine (L-norleucine) is a 2-aminohexanoic acid is an alpha-amino acid that is caproic acid substituted by an amino group at position 2. It derives from a hexanoic acid. It is used experimentally to study protein structure and function. Norleucin...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)



Vapiprost is a potent dicyclopentadiene thromboxane receptor antagonist that was being developed by Glaxo Wellcome in Japan. Vapiprost has been shown to be a potent and specific thromboxane (Tx)A2 receptor blocking drug in vitro using platelets and b...
Status:
US Approved Rx (2024)
First approved in 1995

Class (Stereo):
CHEMICAL (ACHIRAL)



Mycophenolic acid (MPA) possesses antibacterial, antifungal, antiviral, immunosuppressive and anticancer properties. Mycophenolic acid (MPA) is a fungal metabolite that was initially discovered by Bartolomeo Gosio in 1893 as an antibiotic against ant...
Status:
US Approved Rx (2024)
First approved in 1995

Class (Stereo):
CHEMICAL (ACHIRAL)



Mycophenolic acid (MPA) possesses antibacterial, antifungal, antiviral, immunosuppressive and anticancer properties. Mycophenolic acid (MPA) is a fungal metabolite that was initially discovered by Bartolomeo Gosio in 1893 as an antibiotic against ant...
Status:
US Approved Rx (2024)
First approved in 1995

Class (Stereo):
CHEMICAL (ACHIRAL)



Mycophenolic acid (MPA) possesses antibacterial, antifungal, antiviral, immunosuppressive and anticancer properties. Mycophenolic acid (MPA) is a fungal metabolite that was initially discovered by Bartolomeo Gosio in 1893 as an antibiotic against ant...

Showing 1 - 10 of 20 results