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Development Status

Investigational

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Possibly Marketed Outside US

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Approval Year

2011

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Unknown

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Sigma-tau

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NAMITECAN

X34Z8N66T3

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Status:

Investigational

Class (Stereo):

CHEMICAL (ABSOLUTE)

Namitecan (ST1968) is a camptothecin analogue being developed by sigma-tau (a subsidiary of Alfasigma) in Switzerland for the treatment of cancer. Namitecan, a novel hydrophilic camptothecin analog of the 7-oxyiminomethyl series, was selected for cli...

nical development on the basis of its promising preclinical efficacy. Namitecan is a topoisomerase I inhibitor. Namitecan exhibited an acceptable toxicity profile, with neutropenia being the dose-limiting toxic effect, and clinical benefit was appreciable in patients with different tumor types, particularly bladder and endometrium carcinomas.

BENZIMIDAZOLE

E24GX49LD8

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Status:

Possibly Marketed Outside US

First approved in 2011

Class (Stereo):

CHEMICAL (ACHIRAL)

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