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Showing 1 - 6 of 6 results
Status:
US Approved OTC
Source:
21 CFR 346.10(e) anorectal:local anesthetic dyclonine hydrochloride
Source URL:
First approved in 1955
Source:
DYCLONE by ASTRAZENECA
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Dyclonine is an local anesthetic used to provide topical anesthesia to mucous membranes through sodium channel inhibition. It is the active ingredient in Sucrets, an over-the-counter throat lozenge. It has been used as a local anesthetic agent prior to laryngoscopy, bronchoscopy, esophagoscopy, or endotracheal intubation. However, oral solutions no longer are commercially available in the US. Recently, additional activities of dyclonine have been discovered. Dyclonine represents a novel therapeutic strategy that can potentially be repurposed for the treatment of Friedreich's ataxia. Dyclonine enhances the cytotoxic effect of proteasome inhibitors on cancer and multiple myeloma cells.
Status:
Investigational
Source:
INN:dexivacaine [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Dexivacaine is a local anesthetic drug that has minimal and non-significant side effects.
Status:
Possibly Marketed Outside US
Source:
NDA021041
(1999)
Source URL:
First approved in 1999
Source:
NDA021041
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Glyceryl trielaidate (glycerol trielaidate, or trielaidin) is a triglyceride formed by esterification of the three hydroxy groups of glycerol with elaidic acid.
Status:
US Approved OTC
Source:
21 CFR 346.10(e) anorectal:local anesthetic dyclonine hydrochloride
Source URL:
First approved in 1955
Source:
DYCLONE by ASTRAZENECA
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Dyclonine is an local anesthetic used to provide topical anesthesia to mucous membranes through sodium channel inhibition. It is the active ingredient in Sucrets, an over-the-counter throat lozenge. It has been used as a local anesthetic agent prior to laryngoscopy, bronchoscopy, esophagoscopy, or endotracheal intubation. However, oral solutions no longer are commercially available in the US. Recently, additional activities of dyclonine have been discovered. Dyclonine represents a novel therapeutic strategy that can potentially be repurposed for the treatment of Friedreich's ataxia. Dyclonine enhances the cytotoxic effect of proteasome inhibitors on cancer and multiple myeloma cells.
Status:
Investigational
Source:
INN:dexivacaine [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Dexivacaine is a local anesthetic drug that has minimal and non-significant side effects.
Status:
Possibly Marketed Outside US
Source:
NDA021041
(1999)
Source URL:
First approved in 1999
Source:
NDA021041
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Glyceryl trielaidate (glycerol trielaidate, or trielaidin) is a triglyceride formed by esterification of the three hydroxy groups of glycerol with elaidic acid.