Lumefantrine is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy (Coartem tablets). Lumefantrine is a blood schizonticide active against erythrocytic stages of Pl...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Minocycline is a tetracycline analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant staphylococcus infections. Minocycline has many brand names one of them is minocin, Minocin...
Class (Stereo):
CHEMICAL (RACEMIC)
Primaquine is a oral medication used to treat and prevent malaria and to treat Pneumocystis pneumonia. Specifically it is used for malaria due to Plasmodium vivax and Plasmodium ovale along with other medications and for prevention if other options c...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, Plasmodium falciparum and Plasmodium vivax, from reproducing once it is in the red blood cells. Proguanil in combination with atovaquone are marked under the...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Quinidine is a pharmaceutical agent that acts as a class I antiarrhythmic agent (Ia) in the heart. It is a stereoisomer of quinine, originally derived from the bark of the cinchona tree. The drug causes increased action potential duration, as well as...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Oxytetracycline, a tetracycline analog isolated from the actinomycete streptomyces rimosus, was the second of the broad-spectrum tetracycline group of antibiotics to be discovered The drug is used for the prophylaxis and local treatment of superficia...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Amopyroquine, a Mannich base derivative of 4-aminoquinolines, is an antimalarial agent. Amopyroquine was found to be effective against chloroquine-resistant strains of Plasmodium falciparum in Central Africa and was being reintroduced in that contine...
Pyronaridine was developed in China and has been registered in that country since the 1980s. Outside China, none of the existing formulations is registered because of the failure to meet international regulatory standards. Pyronaridine is generally a...
Arteflene is the sesquiterpene peroxide. It is a synthetic derivative of yingzhaosuwas. Arteflene found negative in a battery of mutagenicity tests. It had low acute toxicity after oral or subcutaneous administration in pre-clinical studies. Experime...