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US Approved Rx

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HMG-CoA reductase

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1974

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1996

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Cardiovascular diseases

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Hyperlipidemia

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Contrast agent

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Parke Davis|Warner-Lambert

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LIPID MODIFYING AGENTS

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LIPID MODIFYING AGENTS, COMBINATIONS

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ATC Level 4

HMG CoA reductase inhibitors

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HMG CoA reductase inhibitors in combination with other lipid modifying agents

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HMG CoA reductase inhibitors, other combinations

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Showing 1 - 10 of 13 results

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ATORVASTATIN

A0JWA85V8F

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Status:

US Approved Rx (2023)

First approved in 1996

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

HMG-CoA reductase

Conditions:

Cardiovascular diseases

Atorvastatin calcium (LIPITOR®) is a pyrrole and heptanoic acid derivative, a synthetic lipid-lowering agent. Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the c...

onversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Atorvastatin is used to reduce serum levels of LDL(low-density lipoprotein)-cholesterol; apolipoprotein B; and triglycerides and to increase serum levels of HDL(high-density lipoprotein)-cholesterol in the treatment of hyperlipidemias and prevention of cardiovascular disease in patients with multiple risk factors.

MEGLUMINE

6HG8UB2MUY

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Status:

US Previously Marketed

First approved in 1974

Class (Stereo):

CHEMICAL (ABSOLUTE)

Conditions:

Meglumine (N-methyl-D-glucamine) is a poorly metabolized derivative of sorbitol that has regulatory acceptance as a benign excipient for drug formulation to increase aqueous solubility of lipophilic drugs and improve their absorption. In conjugated f...

orm meglumine is used as a contrast agent.

Atorvastatin strontium pentahydrate

5F4N5Y2B7Y

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Status:

US Approved Rx (2023)

First approved in 1996

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

HMG-CoA reductase

Conditions:

Cardiovascular diseases

Atorvastatin calcium (LIPITOR®) is a pyrrole and heptanoic acid derivative, a synthetic lipid-lowering agent. Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the c...

onversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Atorvastatin is used to reduce serum levels of LDL(low-density lipoprotein)-cholesterol; apolipoprotein B; and triglycerides and to increase serum levels of HDL(high-density lipoprotein)-cholesterol in the treatment of hyperlipidemias and prevention of cardiovascular disease in patients with multiple risk factors.

ATORVASTATIN LYSINE

WK4UJ44C6N

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Status:

US Approved Rx (2023)

First approved in 1996

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

HMG-CoA reductase

Conditions:

Cardiovascular diseases

Atorvastatin calcium (LIPITOR®) is a pyrrole and heptanoic acid derivative, a synthetic lipid-lowering agent. Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the c...

onversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Atorvastatin is used to reduce serum levels of LDL(low-density lipoprotein)-cholesterol; apolipoprotein B; and triglycerides and to increase serum levels of HDL(high-density lipoprotein)-cholesterol in the treatment of hyperlipidemias and prevention of cardiovascular disease in patients with multiple risk factors.

ATORVASTATIN CALCIUM PROPYLENE GLYCOL SOLVATE

YRZ789OWMI

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Status:

US Approved Rx (2023)

First approved in 1996

Class (Stereo):

CHEMICAL (EPIMERIC)

Targets:

HMG-CoA reductase

Conditions:

Cardiovascular diseases

Atorvastatin calcium (LIPITOR®) is a pyrrole and heptanoic acid derivative, a synthetic lipid-lowering agent. Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the c...

onversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Atorvastatin is used to reduce serum levels of LDL(low-density lipoprotein)-cholesterol; apolipoprotein B; and triglycerides and to increase serum levels of HDL(high-density lipoprotein)-cholesterol in the treatment of hyperlipidemias and prevention of cardiovascular disease in patients with multiple risk factors.

ATORVASTATIN STRONTIUM

AMJ4WWI6NM

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Status:

US Approved Rx (2023)

First approved in 1996

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

HMG-CoA reductase

Conditions:

Cardiovascular diseases

Atorvastatin calcium (LIPITOR®) is a pyrrole and heptanoic acid derivative, a synthetic lipid-lowering agent. Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the c...

onversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Atorvastatin is used to reduce serum levels of LDL(low-density lipoprotein)-cholesterol; apolipoprotein B; and triglycerides and to increase serum levels of HDL(high-density lipoprotein)-cholesterol in the treatment of hyperlipidemias and prevention of cardiovascular disease in patients with multiple risk factors.

ATORVASTATIN MAGNESIUM

IVW98J023E

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Status:

US Approved Rx (2023)

First approved in 1996

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

HMG-CoA reductase

Conditions:

Cardiovascular diseases

Atorvastatin calcium (LIPITOR®) is a pyrrole and heptanoic acid derivative, a synthetic lipid-lowering agent. Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the c...

onversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Atorvastatin is used to reduce serum levels of LDL(low-density lipoprotein)-cholesterol; apolipoprotein B; and triglycerides and to increase serum levels of HDL(high-density lipoprotein)-cholesterol in the treatment of hyperlipidemias and prevention of cardiovascular disease in patients with multiple risk factors.

ATORVASTATIN CALCIUM ANHYDROUS

C0GEJ5QCSO

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Status:

US Approved Rx (2023)

First approved in 1996

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

HMG-CoA reductase

Conditions:

Cardiovascular diseases

Atorvastatin calcium (LIPITOR®) is a pyrrole and heptanoic acid derivative, a synthetic lipid-lowering agent. Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the c...

onversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Atorvastatin is used to reduce serum levels of LDL(low-density lipoprotein)-cholesterol; apolipoprotein B; and triglycerides and to increase serum levels of HDL(high-density lipoprotein)-cholesterol in the treatment of hyperlipidemias and prevention of cardiovascular disease in patients with multiple risk factors.

ATORVASTATIN SODIUM

DN43058TIV

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Status:

US Approved Rx (2023)

First approved in 1996

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

HMG-CoA reductase

Conditions:

Cardiovascular diseases

Atorvastatin calcium (LIPITOR®) is a pyrrole and heptanoic acid derivative, a synthetic lipid-lowering agent. Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the c...

onversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Atorvastatin is used to reduce serum levels of LDL(low-density lipoprotein)-cholesterol; apolipoprotein B; and triglycerides and to increase serum levels of HDL(high-density lipoprotein)-cholesterol in the treatment of hyperlipidemias and prevention of cardiovascular disease in patients with multiple risk factors.

ATORVASTATIN CALCIUM TRIHYDRATE

48A5M73Z4Q

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Status:

US Approved Rx (2023)

First approved in 1996

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

HMG-CoA reductase

Conditions:

Cardiovascular diseases

Atorvastatin calcium (LIPITOR®) is a pyrrole and heptanoic acid derivative, a synthetic lipid-lowering agent. Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the c...

onversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. Atorvastatin is used to reduce serum levels of LDL(low-density lipoprotein)-cholesterol; apolipoprotein B; and triglycerides and to increase serum levels of HDL(high-density lipoprotein)-cholesterol in the treatment of hyperlipidemias and prevention of cardiovascular disease in patients with multiple risk factors.

Showing 1 - 10 of 13 results

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