Inxight Drugs

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Return Home Inxight Drugs

Home
Browse Drugs
Search
- Structure Search
- Sequence Search
Downloads
About

Show Filters

Hide Filters

Development Status

US Approved OTC

2

Other

1

All Match

Any Match

Exclude Selected

Exclude Selected

Primary Target

Sodium channel protein type 10 subunit alpha

2

Chymotrypsin C

1

Elastase 1

1

Leukocyte elastase

1

All Match

Any Match

Exclude Selected

Exclude Selected

Highest Phase

Approved

2

All Match

Any Match

Exclude Selected

Exclude Selected

Approval Year

1895

2

Unknown

1

All Match

Any Match

Exclude Selected

Exclude Selected

Condition

Burn

2

Canker sores

2

Hemorrhoids

2

Otitis media

2

Sore mouth

2

All Match

Any Match

Exclude Selected

Exclude Selected

Treatment Modality

Palliative

2

All Match

Any Match

Exclude Selected

Exclude Selected

Originator

Ritsert, E

2

Collie, N.|Myers, W.S.

1

All Match

Any Match

Exclude Selected

Exclude Selected

Substance Class

Chemical

3

All Match

Any Match

Exclude Selected

Exclude Selected

Code System

CAS

3

EPA CompTox

3

FDA UNII

3

NSC

3

PUBCHEM

3

All Match

Any Match

Exclude Selected

Exclude Selected

ATC Level 1

CARDIOVASCULAR SYSTEM

1

DERMATOLOGICALS

1

NERVOUS SYSTEM

1

RESPIRATORY SYSTEM

1

All Match

Any Match

Exclude Selected

Exclude Selected

ATC Level 2

ANESTHETICS

1

ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.

1

THROAT PREPARATIONS

1

VASOPROTECTIVES

1

All Match

Any Match

Exclude Selected

Exclude Selected

ATC Level 3

AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE

1

ANESTHETICS, LOCAL

1

ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.

1

THROAT PREPARATIONS

1

All Match

Any Match

Exclude Selected

Exclude Selected

ATC Level 4

Anesthetics for topical use

1

Anesthetics, local

1

Esters of aminobenzoic acid

1

Local anesthetics

1

All Match

Any Match

Exclude Selected

Exclude Selected

Substance Form

Principal Form

2

Salts, Hydrates, Esters, etc.

1

All Match

Any Match

Exclude Selected

Exclude Selected

Showing 1 - 3 of 3 results

First page disabled
Previous page disabled
1
Next page disabled
Next page disabled

BENZOCAINE

U3RSY48JW5

Export Data
Search for Structure

Status:

US Approved OTC

First marketed in 1895

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium channel protein type 10 subunit alpha

Conditions:

Benzocaine is a local anesthetic. It acts by blocking voltage-gated sodium ion channels in nerve endings. Benzocaine is available over-the counter for local anesthesia of oral and pharyngeal mucous membranes (sore throat, cold sores, mouth ulcers, to...

othache, sore gums, denture irritation), otic pain, and as a local anesthetic for surgical or diagnostic procedures. As a spray, benzocaine is used for temporary relief of pain and itching associated with minor burns, sunburn, minor cuts or scrapes, insect bites, or minor skin irritations. Topical application of benzocaine to gums or mouth may cause rare, but serious and potentially fatal adverse effect methemoglobinemia.

4-HYDROXY-6-METHYL-2-PYRONE

S1S883S4EE

Export Data
Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Leukocyte elastase

Conditions:

4-Hydroxy-6-methyl-2-pyrone (also known as triacetic acid lactone) is a precursor of paragloboside contributing to insect and disease resistance of plant Gerbera hybrida and was recently demonstrated to be a potential platform chemical. 4-Hydroxy-6-m...

ethyl-2-pyrone is an isolated from the fungus, Hypoxylon investing, in 2014 which has not been extensively investigated for pharmacological activity. 4-Hydroxy-6-methyl-2-pyrone is a useful metabolite for analytical and bioassay dereplication of crude microbial extracts.

BENZOCAINE HYDROCHLORIDE

OG625Z9LEO

Export Data
Search for Structure

Status:

US Approved OTC

First marketed in 1895

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium channel protein type 10 subunit alpha

Conditions:

Benzocaine is a local anesthetic. It acts by blocking voltage-gated sodium ion channels in nerve endings. Benzocaine is available over-the counter for local anesthesia of oral and pharyngeal mucous membranes (sore throat, cold sores, mouth ulcers, to...

othache, sore gums, denture irritation), otic pain, and as a local anesthetic for surgical or diagnostic procedures. As a spray, benzocaine is used for temporary relief of pain and itching associated with minor burns, sunburn, minor cuts or scrapes, insect bites, or minor skin irritations. Topical application of benzocaine to gums or mouth may cause rare, but serious and potentially fatal adverse effect methemoglobinemia.

HHS VULNERABILITY DISCLOSURE

For language access assistance, contact the NCATS Public Information Officer

National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966


			version 1.1