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US Approved Rx

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Approval Year

2019

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Ardelyx Inc.

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TENAPANOR

WYD79216A6

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Status:

US Approved Rx (2019)

First approved in 2019

Class (Stereo):

CHEMICAL (ABSOLUTE)

Tenapanor is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3 and reduces sodium absorption in the GI tract, thus increasing intestinal fluid. Ardelyx has completed Phase 3 development of tenapanor for the treatment of irritable bowel sy...

ndrome with constipation (IBS-C) and submitted a new drug application to the U.S. Food and Drug Administration for the treatment of patients with IBS-C. In addition, tenapanor successfully completed phase III clinical trial for the treatment of hyperphosphatemia in people with end-stage renal disease who are on dialysis and RDX013, a potassium secretagogue program for the potential treatment of high potassium, or hyperkalemia, a problem among certain patients with kidney and/or heart disease.

BMS-284640

XP87V064PV

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Status:

Other

Class (Stereo):

CHEMICAL (ABSOLUTE)

TENAPANOR HYDROCHLORIDE

50605O2ZNS

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Status:

US Approved Rx (2019)

First approved in 2019

Class (Stereo):

CHEMICAL (ABSOLUTE)

Tenapanor is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3 and reduces sodium absorption in the GI tract, thus increasing intestinal fluid. Ardelyx has completed Phase 3 development of tenapanor for the treatment of irritable bowel sy...

ndrome with constipation (IBS-C) and submitted a new drug application to the U.S. Food and Drug Administration for the treatment of patients with IBS-C. In addition, tenapanor successfully completed phase III clinical trial for the treatment of hyperphosphatemia in people with end-stage renal disease who are on dialysis and RDX013, a potassium secretagogue program for the potential treatment of high potassium, or hyperkalemia, a problem among certain patients with kidney and/or heart disease.

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