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Showing 1 - 2 of 2 results
Status:
Investigational
Source:
NCT01459926: Phase 2 Interventional Completed Opioid Induced Constipation
(2011)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Axelopran (previously known as TD-1211), a peripherally selective, multivalent µ-opioid receptor antagonist that is under development by Theravance Biopharma. This drug participated in phase II clinical trials in subjects with opioid-induced constipation. The most common adverse events were abdominal pain, nausea, and diarrhea. There were no indications of opioid withdrawal effects or reductions in opioid analgesia in patients treated with axelopran.
Status:
Investigational
Source:
NCT01459926: Phase 2 Interventional Completed Opioid Induced Constipation
(2011)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Axelopran (previously known as TD-1211), a peripherally selective, multivalent µ-opioid receptor antagonist that is under development by Theravance Biopharma. This drug participated in phase II clinical trials in subjects with opioid-induced constipation. The most common adverse events were abdominal pain, nausea, and diarrhea. There were no indications of opioid withdrawal effects or reductions in opioid analgesia in patients treated with axelopran.
