U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 71 - 80 of 186 results

Status:
Investigational
Source:
INN:lobuprofen [INN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Lobuprofen is an ester type analgesic, in which the acid moiety (ibuprofen) has peripheral analgesic activity and the alcohol moiety (mCPPol) has central analgesic activity.
Status:
Investigational
Source:
INN:enprazepine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Enprazepine is an antidepressant.
Status:
Investigational
Source:
INN:flutomidate [INN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Flutomidate was studied as a hypnotic agent. Information about the current use of this agent is not available.
Status:
Investigational
Source:
INN:benhepazone
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Benhepazone (also known as RCH-314) possessed potent analgesic and anti-inflammatory activities. Information about the nowadays use of this compound is not available.
Status:
Investigational
Source:
INN:moxadolen
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Moxadolen is tricyclo-[5.2.1.0.2.6endo]decenone derivative. Moxadolen pharmacokinetics were investigated after oral application in male Wistar rats. The compound is extensively absorbed and mainly renally eliminated. Within 60 h, 63% of the activity is recovered in urine and feces. After 12 h 27% of the activity is eliminated (application in polyethylene glycol). The highest total concentration of the activity in the plasma is found after 2 h, the highest of the unchanged drug is found after 1 h. The half-life is 2.9 h.
Status:
Investigational
Source:
INN:paridocaine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Paridocaine was developed as a local anesthetic. Information about the current use of this drug is not available.
Status:
Investigational
Source:
INN:iotranic acid
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Iotranic Acid is triiodobenzoic acid derivative with potential application as new cholangiographic contrast media for liver imaging
Status:
Investigational
Source:
INN:verilopam [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Verilopam is a potent analgesic.
Status:
Investigational
Source:
INN:dexproxibutene [INN]
Source URL:

Class (Stereo):
CHEMICAL (UNKNOWN)

Dexproxibutene is an experimental agent structurally related to propoxyphene. It is an analgesic agent. Dexproxibutene is not very effective in rheumatoid arthritis pain relief. It is intermediate in effectiveness between distalgesic, codis, aspirin and placebo.
Status:
Investigational
Source:
INN:flutemazepam
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Flutemazepam is a benzodiazepine binding-site agonist and has hypnotic, anticonvulsant and anxiolytic activity. Flutemazepam was found very effective for the treatment of severe states of anxiety