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US Previously Marketed

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Primary Target

Acetylcholinesterase

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Muscarinic acetylcholine receptor M2

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Approved

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1951

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Muscle contractions

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Palliative

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TRIETHYLGALLAMINE

VYJ027LZ05

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Status:

US Previously Marketed

First approved in 1951

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Acetylcholinesterase

Muscarinic acetylcholine receptor M2

Conditions:

Muscle contractions

Gallamine triethiodide is a synthetic nondepolarizing blocking drug, which is allosteric antagonist of muscarinic M2 acetylcholine receptor and inhibitor of acetylcholinesterase. It was used under brand name flaxedil to stabilize muscle contractions ...

during surgical procedures. However, this usage was discontinued. It was shown, that gallamine caused tachycardia by depressing the vagus nerve and, occasionally, hypertension and increased cardiac output.

GALLAMINE TRIETHIODIDE

Q3254X40X2

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Search for Structure

Status:

US Previously Marketed

First approved in 1951

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Acetylcholinesterase

Muscarinic acetylcholine receptor M2

Conditions:

Muscle contractions

Gallamine triethiodide is a synthetic nondepolarizing blocking drug, which is allosteric antagonist of muscarinic M2 acetylcholine receptor and inhibitor of acetylcholinesterase. It was used under brand name flaxedil to stabilize muscle contractions ...

during surgical procedures. However, this usage was discontinued. It was shown, that gallamine caused tachycardia by depressing the vagus nerve and, occasionally, hypertension and increased cardiac output.

HHS VULNERABILITY DISCLOSURE

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