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Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Dolastatin 10 is an unusual peptide of marine origin which binds to tubulin, inhibits microtubule assembly, resulting in the formation of tubulin aggregates and inhibition of mitosis. Dolastatin 10 has been used in trials phase II studying the treatm...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Tanespimycin (17-allylamino-17-demethoxygeldanamycin,
17-AAG) is a synthetic analogue of geldanamycin, an antibiotic
first purified in 1970 from Streptomyces hygroscopicus. Tanespimycin is an Hsp90 inhibitor that has demonstrated the potential to dis...