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Showing 1 - 3 of 3 results
Status:
Investigational
Source:
NCT00725933: Phase 1 Interventional Completed Advanced Solid Tumors
(2008)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
2,4-Diamino-6-hydroxypyrimidine is a selective, specific inhibitor of GTP cyclohydrolase I, a rate-limiting enzyme for the de novo biosynthesis of biopterin. Experiments in rats have shown that 4-Diamino-6-hydroxypyrimidine possesses protective effects against postburn Staphylococcus aureus sepsis.
