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1921

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Schizophrenia

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Primary

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Anderson, T.

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DIETHYL (ETHOXYMETHYLENE)MALONATE

6KF8220SZ8

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

PIPERIDINE

67I85E138Y

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Conditions:

Piperidine is a normal constituent in mammalian brain. It was shown to affect synaptic mechanism in the CNS, and influence neural mechanisms governing regulation of emotional behavior, sleeping, and extrapyramidal function. In addition, there are enz...

yme systems within the brain that synthesize and metabolize piperidine, and uptake and storage mechanisms for piperidine are found in the nerve endings. Piperidine, which proved to be a highly effective “antipsychotomimetic” agent in rats, has been reported to bring about substantial improvement in a variety of schizophrenic patients.

PHOSPHORUS

27YLU75U4W

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Status:

US Previously Marketed

First marketed in 1921

Class (Stereo):

CHEMICAL (ACHIRAL)

Phosphorus is a chemical element with symbol P and atomic number 15. Phosphorus is essential for life (compounds containing the phosphate ion) are a component of DNA, RNA, ATP, and phospholipids. Elemental phosphorus exists in many allotropic forms, ...

three major allotropes are white, red and black. Red phosphorus is a component of matchbook strike plates and is used as an ingredient in certain commercial rat and cockroach poisons. Red phosphorus is used in the manufacture of pyrotechnics, safety matches, semiconductors, fertilizers, pesticides, incendiary shells, smoke bombs, and tracer bullets. It is also used in organic synthesis reactions and in the manufacture of phosphoric acid, phosphine, phosphoric anhydride, phosphorus pentachloride, and phosphorus trichloride. Red phosphorus is also used in electroluminescent coatings and in flame retardants for polymers.

PIPERIDINE HYDROCHLORIDE

5MY66P6N3M

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Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

Conditions:

Piperidine is a normal constituent in mammalian brain. It was shown to affect synaptic mechanism in the CNS, and influence neural mechanisms governing regulation of emotional behavior, sleeping, and extrapyramidal function. In addition, there are enz...

yme systems within the brain that synthesize and metabolize piperidine, and uptake and storage mechanisms for piperidine are found in the nerve endings. Piperidine, which proved to be a highly effective “antipsychotomimetic” agent in rats, has been reported to bring about substantial improvement in a variety of schizophrenic patients.

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