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Ritsert, E

2

Pfizer

420

Eli Lilly

237

Merck

216

GlaxoSmithKline

193

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Development Status

US Approved OTC

2

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Primary Target

Sodium channel protein type 10 subunit alpha

2

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Approved

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1895

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Burn

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Canker sores

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Hemorrhoids

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Otitis media

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Palliative

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Chemical

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CAS

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ANESTHETICS

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ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.

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ATC Level 3

AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE

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ANESTHETICS, LOCAL

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ATC Level 4

Anesthetics for topical use

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Esters of aminobenzoic acid

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BENZOCAINE

U3RSY48JW5

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Status:

US Approved OTC

First marketed in 1895

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium channel protein type 10 subunit alpha

Conditions:

Benzocaine is a local anesthetic. It acts by blocking voltage-gated sodium ion channels in nerve endings. Benzocaine is available over-the counter for local anesthesia of oral and pharyngeal mucous membranes (sore throat, cold sores, mouth ulcers, to...

othache, sore gums, denture irritation), otic pain, and as a local anesthetic for surgical or diagnostic procedures. As a spray, benzocaine is used for temporary relief of pain and itching associated with minor burns, sunburn, minor cuts or scrapes, insect bites, or minor skin irritations. Topical application of benzocaine to gums or mouth may cause rare, but serious and potentially fatal adverse effect methemoglobinemia.

BENZOCAINE HYDROCHLORIDE

OG625Z9LEO

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Status:

US Approved OTC

First marketed in 1895

Class (Stereo):

CHEMICAL (ACHIRAL)

Targets:

Sodium channel protein type 10 subunit alpha

Conditions:

Benzocaine is a local anesthetic. It acts by blocking voltage-gated sodium ion channels in nerve endings. Benzocaine is available over-the counter for local anesthesia of oral and pharyngeal mucous membranes (sore throat, cold sores, mouth ulcers, to...

othache, sore gums, denture irritation), otic pain, and as a local anesthetic for surgical or diagnostic procedures. As a spray, benzocaine is used for temporary relief of pain and itching associated with minor burns, sunburn, minor cuts or scrapes, insect bites, or minor skin irritations. Topical application of benzocaine to gums or mouth may cause rare, but serious and potentially fatal adverse effect methemoglobinemia.

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