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Showing 1 - 10 of 12 results

Status:
US Approved OTC
First approved in 1948

Class (Stereo):
CHEMICAL (RACEMIC)



Doxylamine is an antihistamine commonly used as a sleep aid. This drug is also used to relieve symptoms of hay fever (allergic rhinitis), hives (rash or itching), and other allergic reactions. Doxylamine is a member of the ethanolamine class of antih...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Mofegiline (MDL 72,974A or (E)-2-(4-fluorophenethyl)-3-fluoroallylamine, hydrochloride), is a selective and irreversible inhibitor of monoamine oxidase type B (MAO-B) both in vitro and in vivo. In addition, mofegiline inhibits semicarbazide-sensitive...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Tropanserin (MDL 72422) is a potent and selective 5-HT3 receptor antagonist. It was investigated as a drug for the treatment of migraine. MDL 72222 was shown to be an effective antimigraine agent in a double-blind placebo-controlled study.
Status:
Investigational

Class (Stereo):
CHEMICAL (RACEMIC)



Glemanserin is a selective antagonist of the 5-HT2A receptor. It was tested in a clinical trial, in patients with generalized anxiety disorder, however, it did not demonstrate significant anxiolytic effects.
Status:
US Previously Marketed
First approved in 1942

Class (Stereo):
CHEMICAL (ABSOLUTE)



Etafedrine, a sympathomimetic agent that acts on the sympathetic receptors of the bronchial tree relaxing spasm in a manner similar to that of ephedrine, is a bronchodilator and a selective β2-adrenoreceptor agonist. Contraction of the guinea pig tra...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)



Enoximone is an inhibitor of PDE3, which is used for the treatment of congestive heart failure. Also enoximone was shown to inhibit PDH in cardiac myocytes. The inhibition was shown to occur secondary to stimulating fatty acid oxidation
Status:
US Approved OTC
First approved in 1948

Class (Stereo):
CHEMICAL (RACEMIC)



Doxylamine is an antihistamine commonly used as a sleep aid. This drug is also used to relieve symptoms of hay fever (allergic rhinitis), hives (rash or itching), and other allergic reactions. Doxylamine is a member of the ethanolamine class of antih...
Status:
US Approved OTC
First approved in 1948

Class (Stereo):
CHEMICAL (RACEMIC)



Doxylamine is an antihistamine commonly used as a sleep aid. This drug is also used to relieve symptoms of hay fever (allergic rhinitis), hives (rash or itching), and other allergic reactions. Doxylamine is a member of the ethanolamine class of antih...
Status:
US Approved OTC
First approved in 1948

Class (Stereo):
CHEMICAL (RACEMIC)



Doxylamine is an antihistamine commonly used as a sleep aid. This drug is also used to relieve symptoms of hay fever (allergic rhinitis), hives (rash or itching), and other allergic reactions. Doxylamine is a member of the ethanolamine class of antih...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Tropanserin (MDL 72422) is a potent and selective 5-HT3 receptor antagonist. It was investigated as a drug for the treatment of migraine. MDL 72222 was shown to be an effective antimigraine agent in a double-blind placebo-controlled study.

Showing 1 - 10 of 12 results