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Showing 1 - 10 of 47 results

Status:
US Approved Rx (2012)
First approved in 1994

Class (Stereo):
CHEMICAL (ACHIRAL)



Penciclovir (DENAVIR®) is a synthetic acyclic guanine derivative with antiviral activity, mainly used to treat infections from herpes simplex virus (HSV) types 1 and 2. In cells infected with HSV-1 or HSV-2, the viral thymidine kinase phosphorylates ...
Status:
US Approved Rx (2009)
First approved in 1993

Class (Stereo):
CHEMICAL (ACHIRAL)



Granisetron is a selective inhibitor of type 3 serotonergic (5-HT3) receptors. The drug is structurally and pharmacologically related to ondansetron, another selective inhibitor of 5-HT3 receptors. The serontonin 5-HT3 receptors are located on the ne...
Status:
US Approved Rx (2011)
First approved in 1991

Class (Stereo):
CHEMICAL (ACHIRAL)



Nabumetone is a naphthylalkanone. Is is a non-selective prostaglandin G/H synthase (a.k.a. cyclooxygenase or COX) inhibitor that acts on both prostaglandin G/H synthase 1 and 2 (COX-1 and -2). Prostaglandin G/H synthase catalyzes the conversion of ar...
Status:
US Approved Rx (2021)
First approved in 1987

Class (Stereo):
CHEMICAL (ABSOLUTE)



Mupirocin (BACTROBAN®) is an antibiotic from a strain of Pseudomonas fluorescens. It has shown excellent activity against gram-positive staphylococci and streptococci. The antibiotic is used primarily for the treatment of primary and secondary skin d...
Status:
US Approved Rx (2012)
First approved in 1973

Class (Stereo):
CHEMICAL (ABSOLUTE)



Amoxicillin is one of the widely prescribed antibacterial agents, which was discovered by scientists at Beecham Research Laboratories in 1972. In the US GlaxoSmithKline markets it under the original brand name Amoxil. It is the first line treatment f...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Denbufylline is a selective xanthine derivative that inhibits PDE IV and has bronchodilatory properties. Shown to exhibit negative inotropic effects by acting on verapamil-sensitive sites of Ca2+ channels in guinea pig ventricle papillary muscle inde...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Cipamfylline is a xanthine, a theophylline analogue, and is a potent and selective inhibitor of phosphodiesterase type 4 (PDE-4). Cipamfylline was tested in patients with a diagnosis of atopic dermatitis and in two human models of acute and chronic i...
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

N,N-Dimethyl-2-(2-phenylacetamido)acetamide is an acyl glycine derivative. N,N-Dimethyl-2-(2-phenylacetamido)acetamide is GLP-1 Receptor Agonist.
SB-206606 (better known as BRL-37344) was developed by Beecham Pharmaceuticals and is currently licensable from GlaxoSmithKline. SB-206606 is an agonist for the Beta-3 adrenergic receptor with an EC 50 value of 17 nM (human B3AR expressed in CHO cell...
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

L-Amoxicillin is an isomer of amoxicillin also known as 'amoxicillin related compound B'. It is considered an impurity.