U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

    {{facet.count}}
    {{facet.count}}

Showing 2421 - 2430 of 13362 results

Status:
Possibly Marketed Outside US
Source:
MARY KAY TIMEWISE REPAIR VOLU-FIRM THE GO SET
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Mica is the name of a group of 37 phyllosilicate minerals with layered or lamellar texture. Mica is widely distributed and found in igneous, metamorphic and sedimentary regimes. Large crystals of mica used for various purposes are usually extracted from granite pegmatites. Commercially important micas are muscovite and phlogopite, which are used in various fields. The value of mica is based on several of its unique physical properties. The mica crystal structure forms layers that can be split or laminated into thin sheets, usually causing lamination in the rocks. These sheets are chemically inert, dielectric, elastic, flexible, hydrophilic, insulating, light, plastic, reflective, refracting, resilient and have opacity from transparent to opaque. Mica is stable when exposed to electricity, light, moisture and extreme temperatures. It has excellent electrical properties as an insulator and dielectric and can maintain an electrostatic field while dissipating minimal energy in the form of heat; it can be very thin while maintaining its electrical properties, has a high dielectric breakdown, thermally stable to 500 ° C and resistant to corona discharge. Muscovite, the main mica used in the electrical industry, is used in capacitors that are ideally suited for high frequencies and radio frequencies. Mica dust in the workplace is regarded as a hazardous substance for respiratory exposure above certain concentrations.
Status:
Possibly Marketed Outside US
Source:
Cortizone 10 for Psoriasis
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Methyl ethyl ketone (butanone) is an industrial solvent produced on a large scale. It is used in surface coatings, adhesives, printing inks, chemical intermediates, magnetic tapes, and lube oil dewaxing agents. Methyl ethyl ketone has a fruity odor similar to acetone. It is used as a flavor/fragrance agent in pharmaceuticals and cosmetics.
Status:
Possibly Marketed Outside US
Source:
Canada:INOSINE PRANOBEX
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Inosine is a naturally occurring nucleoside which serves as an intermediate in purine metabolism. The metabolism of purines in humans generates a potent antioxidant compound, uric acid, which is known to be a natural scavenger of both oxygen and nitrogen reactive species as well as having chelator properties. Inosine, as a precursor of uric acid, was shown to have neuroprotective effect in vitro and is being tested in phase III of clinical trials for the treatment of Parkinson disease. The treatment with inosine is belived to prevent or slow the disease.
Status:
Possibly Marketed Outside US
Source:
NCT01425853: Phase 4 Interventional Completed Knee Osteoarthritis
(2011)
Source URL:
First approved in 1997
Source:
NaturVet ArthriSoothe by The Garmon Corporation
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Glucosamine is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Glucosamine is part of the structure of the polysaccharides chitosan and chitin, which compose the exoskeletons of crustaceans and other arthropods, as well as the cell walls of fungi and many higher organisms. Glucosamine is one of the most abundant monosaccharides. It is produced commercially by the hydrolysis of crustacean exoskeletons or, less commonly, by fermentation of a grain such as corn or wheat. Oral glucosamine is a dietary supplement and is not a pharmaceutical drug. It is illegal in the US to market any dietary supplement as a treatment for any disease or condition. Glucosamine is marketed to support the structure and function of joints, and the marketing is targeted to people suffering from osteoarthritis. Commonly sold forms of glucosamine are glucosamine sulfate, glucosamine hydrochloride, and N-acetylglucosamine. Of the three commonly available forms of glucosamine, only glucosamine sulfate is given a "likely effective" rating for treating osteoarthritis. Glucosamine is often sold in combination with other supplements such as chondroitin sulfate and methylsulfonylmethane. Glucosamine, along with commonly used chondroitin, is not routinely prescribed to treat people who have symptomatic osteoarthritis of the knee, as there is insufficient evidence that this treatment is helpful. One clinical study over three years showed that glucosamine in doses of 1500 mg per day is safe to use. Glucosamine with or without chondroitin elevates the international normalized ratio (INR) in individuals who are taking the blood thinner, warfarin. It may also interfere with the efficacy of chemotherapy for treating cancer symptoms. Adverse effects may include stomach upset, constipation, diarrhea, headache, and rash. There are case reports of people who have chronic liver disease and a worsening of their condition with glucosamine supplementation. Glucosamine is naturally present in the shells of shellfish, animal bones, bone marrow, and fungi. D-Glucosamine is made naturally in the form of glucosamine-6-phosphate, and is the biochemical precursor of all nitrogen-containing sugars. Specifically in humans, glucosamine-6-phosphate is synthesized from fructose 6-phosphate and glutamine by glutamine—fructose-6-phosphate transaminase as the first step of the hexosamine biosynthesis pathway. The end-product of this pathway is uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. As the formation of glucosamine-6-phosphate is the first step for the synthesis of these products, glucosamine may be important in regulating their production; however, the way that the hexosamine biosynthesis pathway is actually regulated, and whether this could be involved in contributing to human disease remains unclear.

Showing 2421 - 2430 of 13362 results