U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 161 - 170 of 13362 results


Class (Stereo):
CHEMICAL (ACHIRAL)

Targets:


Dibenzoylmethane (DBM), a minor ingredient in licorice, is a calcium chelator that binds calcium through the β-diketone moiety, and it has been found to increase intracellular calcium concentrations in skeletal muscle cells. Intracellular calcium regulates the binding of Nrf2 to the HO-1 enhancer region. Both Nrf2 and HO-1 have been proposed as potential drug targets to prevent or treat liver disease. Thus was suggested DBM could be a lead/candidate for prevention or treatment of liver diseases. In addition, was found, that dibenzoylmethane inhibits mammary tumorigenesis, lymphomas, and leukemias in mice and it can prevent the formation of tumor-inducing DNA adducts.
Status:
Possibly Marketed Outside US
Source:
Krx Aesthetics All Day Glow Sunblocker by KRX RESOURCES SDN. BHD.
(2024)
Source URL:
First approved in 2024
Source:
Krx Aesthetics All Day Glow Sunblocker by KRX RESOURCES SDN. BHD.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)