U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C6H9NOS
Molecular Weight 143.207
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 4-METHYL-5-THIAZOLEETHANOL

SMILES

CC1=C(CCO)SC=N1

InChI

InChIKey=BKAWJIRCKVUVED-UHFFFAOYSA-N
InChI=1S/C6H9NOS/c1-5-6(2-3-8)9-4-7-5/h4,8H,2-3H2,1H3

HIDE SMILES / InChI
Molecular Formula C6H9NOS
Molecular Weight 143.207
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

2024
711
PubMed

PubMed

TitleDatePubMed
Domain organization in Candida glabrata THI6, a bifunctional enzyme required for thiamin biosynthesis in eukaryotes.
2010-11-16
Variation of some fermentative sulfur compounds in Italian "millesime" classic sparkling wines during aging and storage on lees.
2010-09-08
Synthesis and odor evaluation of five new sulfur-containing ester flavor compounds from 4-ethyloctanoic acid.
2010-07-29
The vitamin B1 metabolism of Staphylococcus aureus is controlled at enzymatic and transcriptional levels.
2009-11-03
New structural insights and molecular-modelling studies of 4-methyl-5-beta-hydroxyethylthiazole kinase from Pyrococcus horikoshii OT3 (PhThiK).
2009-10-01
The ADP-dependent sugar kinase family: kinetic and evolutionary aspects.
2009-07
Combining specificity determining and conserved residues improves functional site prediction.
2009-06-09
The genes and enzymes involved in the biosynthesis of thiamin and thiamin diphosphate in yeasts.
2008
Non-empirical study of the phosphorylation reaction catalyzed by 4-methyl-5-beta-hydroxyethylthiazole kinase: relevance of the theory of intermolecular interactions.
2007-07
Thiazole synthase from Escherichia coli: an investigation of the substrates and purified proteins required for activity in vitro.
2007-06-15
Effect of pH on the Maillard reaction of [13C5]xylose, cysteine, and thiamin.
2007-02-21
Structure of the thiazole biosynthetic enzyme THI1 from Arabidopsis thaliana.
2006-10-13
Recent progress in understanding thiamin biosynthesis and its genetic regulation in Saccharomyces cerevisiae.
2006-08
Biosynthesis of thiamin thiazole: determination of the regiochemistry of the S/O acyl shift by using 1,4-dideoxy-D-xylulose-5-phosphate.
2006-05-19
Vitamin B1 de novo synthesis in the human malaria parasite Plasmodium falciparum depends on external provision of 4-amino-5-hydroxymethyl-2-methylpyrimidine.
2006-01
Chromatographic study of photolysis of aqueous cyanocobalamin solution in presence of vitamins B and C.
2004-01
Patents

Patents

05491241
1
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:27:15 GMT 2025
Edited
by admin
on Mon Mar 31 19:27:15 GMT 2025
Record UNII
3XYV4I47I8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
4-METHYL-5-THIAZOLEETHANOL
FHFI   MI  
Systematic Name English
FEMA NO. 3204
Preferred Name English
HEMINEURINE
Common Name English
NSC-41831
Code English
THIAMINE THIOZOLE
Common Name English
4-METHYL-5-THIAZOLYLETHANOL
Systematic Name English
NSC-23262
Code English
4-METHYL-5-(2-HYDROXYETHYL)THIAZOLE
Systematic Name English
2-(4-METHYL-1,3-THIAZOL-5-YL)ETHANOL
Systematic Name English
2-(4-METHYLTHIAZOLE-5-YL)ETHANOL
Systematic Name English
4-METHYL-5-THIAZOLE ETHANOL [FCC]
Common Name English
5-THIAZOLEETHANOL, 4-METHYL-
Systematic Name English
4-METHYL-5-(.BETA.-HYDROXYETHYL)THIAZOLE
Systematic Name English
5-(2-HYDROXYETHYL)-4-METHYLTHIAZOLE
Systematic Name English
5-(HYDROXYETHYL)-4-METHYLTHIAZOLE
Systematic Name English
4-METHYL-5-THIAZOLEETHANOL [FHFI]
Common Name English
5-(.BETA.-HYDROXYETHYL)-4-METHYLTHIAZOLE
Systematic Name English
4-METHYL-5-THIAZOLEETHANOL [MI]
Common Name English
2-(4-METHYL-5-THIAZOLYL)ETHANOL
Systematic Name English
4-METHYL-5-THIAZOLE ETHANOL
FCC  
Common Name English
SULFUROL
Common Name English
Classification Tree Code System Code
JECFA EVALUATION 4-METHYL-5-THIAZOLEETHANOL
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
Code System Code Type Description
DRUG BANK
DB02969
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
PRIMARY
JECFA MONOGRAPH
964
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
PRIMARY
MERCK INDEX
m7469
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
PRIMARY Merck Index
CHEBI
17957
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
PRIMARY
PUBCHEM
1136
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
PRIMARY
FDA UNII
3XYV4I47I8
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
PRIMARY
CAS
137-00-8
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
PRIMARY
EPA CompTox
DTXSID3044382
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
PRIMARY
MESH
C012572
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
PRIMARY
ECHA (EC/EINECS)
205-272-6
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
PRIMARY
NSC
23262
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
PRIMARY
NSC
41831
Created by admin on Mon Mar 31 19:27:15 GMT 2025 , Edited by admin on Mon Mar 31 19:27:15 GMT 2025
PRIMARY
Related Record Type Details
Structure of GT-1061 FREE BASE
PARENT -> METABOLITE
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966