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Status:
Investigational
Source:
NCT00312286: Phase 2 Interventional Terminated Papillomavirus Infections
(2006)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Epetirimod (S-30563 or TAK-851) is an immunostimulant. The compound is structurally related to the marketed topical imidazoquinoline drug, imiquimod, an agonist of Toll-like receptor 7. Epetirimod was under development with Takeda Pharmaceutical as a topical treatment for cervical high-risk HPV infection and cervical dysplasia. Takeda has discontinued epetirimod development as it did not meet the predefined efficacy end points in a US Phase II trial.
Status:
Investigational
Source:
INN:prifetrastat [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Investigational
Source:
NCT03467100: Phase 1 Interventional Completed Healthy Volunteers
(2018)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
NCT03329885: Phase 1/Phase 2 Interventional Terminated Rheumatoid Arthritis
(2017)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
INN:palatrigine [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Palatrigine (also known as BW A256C) was developed and classified as a novel "slow" class 1C antiarrhythmic agent. Information about the current use of this drug is not available.
Class (Stereo):
CHEMICAL (ACHIRAL)
Droxacin is quinolone antibiotic. It is topoisomerase inhibitor.
Class (Stereo):
CHEMICAL (RACEMIC)
Teflurane was first used in man in 1960. A series of thirty anesthetics completed in the first six months suggested that the teflurane was essentially non-toxic to the circulatory system and to hepatic and renal function. However, when the drug was given at inspired concentrations of 10 % and above, cardiac arrhythmias appeared, increased in severity and significance and systolic and diastolic blood pressures fell in direct proportion to the concentration given. That is why the further development of the teflurane was terminated.
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Rimcazole is a carbazole derivative that acts as a sigma receptor antagonist and studied as potential antipsychotic agent for the treatment of acute schizophrenic patients. In open-clinical trials Rimcazole (BW 234U) appears to be effective in acute schizophrenic patients. However, subsequent clinical trials demonstrated that rimcazole lacked efficacy in schizophrenic patients and it is now primarily used as an experimental tool. In addition to its actions as receptor antagonist, rimcazole also has high affinity for dopamine transporters, and inrecent years it has served as a lead compound for the development of novel dopamine transporter ligands.
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Paraxazone is a monoamine oxidase Inhibitor that was studied as an antidepressant but has never been marketed. Information about the current use of this drug is not available.
