NNC 63-0532 is a potent non-peptide agonist for the KOR-3 (NOP receptor) (EC50 = 305 nM, Ki = 7.3 nM); about a 12-fold increase in selectivity over other receptors. NNC 63-0532 is an nociceptoid drug used in scientific research.

PD-404182 is an inhibitor of bacterial 2-keto-3-deoxyctulosonic acid (KDO) 8-P synthase. It is a virucidal compound that compromises the structural integrity of both hepatitis C virus and human immunodeficiency virus, likely by interacting with a nonlipid structural element of these viruses. In vitro studies revealed that PD-404182 physically disrupts variously pseudotyped lentiviruses and exposes the viral genomic RNA in a time- and temperature-dependent manner. Also, PD-404182 might be a tightly bound, covalent, or an irreversible inhibitor of human dimethylarginine dimethylaminohydrolase 1.

Trimedlure (1,1-dimethylethyl 4- and 5-chloro-2- methylcyclohexanecarboxylate) is a synthetic attractant for the Mediterranean fruit fly that has four trans and four cis structures. The trans-trimedlure isomers are A, B1, B2, and C and cis-trimedlure isomers are V, W, X, and Y. Commercial TML is composed primarily of four trans isomers and lesser quantities of the four cis isomers

BMS 265246 is a potent inhibitor of cyclin dependent kinase 1 and 2. It was under investigation with BristolMyers Squibb in the USA with potential in the treatment of cancer, however, BristolMyers Squibb no longer lists this product on its research and development pipelines which suggests that development of the programme has been discontinued.

BGC 20761 is an orally active, tryptamine analogue that is being developed by BTG as a procognitive antipsychotic for the treatment of schizophrenia. Preclinical development is underway in the US. This serotonin6 and serotonin2A receptor antagonist has nootropic properties with a balance of serotonergic and dopaminergic antagonist activity; BGC 20761 has moderate to low affinity for dopamine2, serotonin2C, histamine1, muscarinic M1-5, and α1 adrenergic receptors, indicating a potentially low propensity to cause serious adverse events.

Ammonium phenolsulfonate is an ingredient of deodorant, possesses antimicrobial properties to help the inhibition of the growth of microorganism of the skin.

2,5-Dimethoxy-4-trifluoromethylamphetamine (DOTFM) is the alpha-methylated analogue of 2C-TFM, a psychedelic drug of the phenethylamine and amphetamine chemical classes. 2,5-Dimethoxy-4-trifluoromethylamphetamine acts as an nanomolar agonist at the 5HT2A and 5HT2C receptors and possess hallucinogenic effects in humans.

Monorden (radicicol), a resorcylic 14-membered lactone, is a macrocyclic natural antibiotic initially isolated from the fungus Monosporium bonorden. Monorden was found to manifest antifungal and antitumor properties. It was shown to be an inhibitor of the v-Src and Ras-Raf-MAPK signaling pathways. Its ability to bind to heat shock protein Hsp90 made it the prototype of a second class of Hsp90 inhibitors, distinct from the chemically unrelated benzoquinone ansamycins. Radicicol inhibited Hsp90 activity by binding to the ATP-binding pocket, subsequently suppressing cell transformation induced by src, ras and mos. Radicicol binds more strongly to Hsp90 than to Grp94, the Hsp90 homolog that resides in the endoplasmic reticulum. In contrast to Hsp90, binding of radicicol to Grp94 requires both the N-terminal ATP/ADP-binding domain as well as the adjacent negatively charged region. Radicicol also specifically binds to yeast Hsp90, Escherichia coli HtpG, with greater homology to bacterial HtpG than to Hsp90 and to and a newly described tumor necrosis factor receptor-interacting protein, Trap-1. Radicicol displayed anti-cancer activity in vitro. It represses estrogen receptor transcriptional activity and inhibits angiogenesis. Radicicol disrupts the ER-Hsp90 heterodimeric complex, thereby generating ER-alpha that is susceptible to ubiquitin/proteasome-induced degradation. Because radicicol is rapidly metabolizes to inactive metabolites in vivo due to its electrophilic nature, no in vivo activity has been observed with this natural product including anti-tumor activity, thus the compound was not considered a viable candidate for clinical evaluation.

α-Ribavirin is an alpha-anomer of ribavirin, a broad spectrum antiviral nucleoside. It is unnatural minor impurity of ribavirin.

R-enantiomer, AG-EE 624 ZW, is more than 100 fold less active than S-enantiomer as hypoglycaemic compound. It is critical to test and control the content of R(–) isomer in repaglinide to assure the quality of tablet. Repaglinide is an oral medication used for blood sugar control in type 2 diabetes mellitus.