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Showing 1 - 10 of 21 results

Status:
US Approved Rx (2021)
First approved in 2000

Class (Stereo):
CHEMICAL (ABSOLUTE)



Lopinavir (ABT-378) is an antiretroviral of the protease inhibitor class. It is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir, under the trade names Kaletra.
Status:
US Approved Rx (2003)
First approved in 1997

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Nelfinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotei...
Status:
US Approved Rx (2004)
First approved in 1987

Class (Stereo):
CHEMICAL (RACEMIC)



Terconazole is an antifungal drug used to treat vaginal yeast infection. Terconazole may exert its antifungal activity by disrupting normal fungal cell membrane permeability. Terconazole and other triazole antifungal agents inhibit cytochrome P450 "1...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Bathocuproine is a promising organic material of a hole blocking layer in organic light-emitting diodes or an electron buffer layer in organic photovoltaic cells. When a thin layer of bathocuproine is inserted between the metal electrode and the orga...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Arno Therapeutics is developing AR-12, an orally available, targeted therapy for cancer and infectious diseases. AR-12 is a potentially first-in-class, orally available, targeted anti-cancer agent that has been shown in preclinical studies to inhibit...
TAK-779 is a selective antagonist of CCR5 receptor, which was initially developed by Takeda for the treatment of HIV infection. However, the development was terminated due to poor oral bioavailability. Also, TAK-779 demonstrated the ability to protec...
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Epicatechin-5-Sulfate is a metabolite of epicatechin. It is patented for inclusion in food formulations intended for weight loss, and treatment of diabetes.
Status:
US Previously Marketed
First approved in 1996

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Indinavir is an antiretroviral drug for the treatment of HIV infection. Indinavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is ...
Status:
US Previously Marketed
First approved in 1995

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Saquinavir (brand names Invirase and Fortovase) is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS. Saquinavir is an inhibitor of HIV protease. HIV protease is an enzyme required for the proteolytic cleavage o...
Status:
US Previously Marketed
First approved in 1992

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

The nucleoside analog 2',3'-dideoxycytidine (ddCyd), also known as Zalcitabine is a nucleoside analog reverse transcriptase inhibitor (NRTI) sold under the trade name Hivid. HIVID is indicated in combination with antiretroviral agents for the treatme...