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Showing 1 - 2 of 2 results
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
A bone resorption inhibitor, A-75943, isolated from the fermentation broth of Streptomyces sp. SANK 61296, was found to be structurally related to cycloheximide, from which A-75943 was prepared chemically.
A-75943 inhibited in vitro bone resorption in a concentration-dependent manner, with maximal nontoxic inhibition greater than 90% at 5ug/ml and an
IC50 of 0.35uM.
Status:
Possibly Marketed Outside US
Source:
21 CFR 355
(2005)
Source URL:
First approved in 2005
Source:
21 CFR 355
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Potassium pyrophosphate is mainly used as an emulsifier, quality improver and metal ion chelating agent. It can be found in herbicidal compositions as a spray adjuvant. It is also used as an anionic dispersant in water-based (latex) paints. GRAS. Potassium Pyrophosphate has being evaluated in phase II clinical trial as an anti-calculus treatment.
