U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 51 - 60 of 216 results

Status:
Possibly Marketed Outside US
Source:
NCT04677712: Phase 4 Interventional Completed Edematous Fibrosclerotic Panniculopathy (EFP)
(2020)
Source URL:
First approved in 2004

Class (Stereo):
CHEMICAL (ACHIRAL)



Phenoxyethanol, also known as Ethylene Glycol Monophenyl Ether, is a glycol ether and bactericide (that functions as a disinfectant, antiseptic or antibiotic) that is primarily used as a preservative in cosmetics and beauty products. It is used as a preservative in vaccines. Phenoxyethanol is included in topical antiseptic solutions, like octenisept used for the treatment of traumatic, acute, chronic, surgical and burn wounds, the treatment of bacterial vaginosis, acne lesions and as the mucous membrane antiseptic.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Gentisic acid ethanolamide is a complexing agent in pharmaceutical parenterals. It is used as a solubilizer in some pharmaceutical preparations and as an antiseptic agent.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)

NAG-thiazoline (NGT) and its derivatives are well-known inhibitors against most b-acetylglucosaminidases (b-GlcNAcases) except for insect and bacterial chitinolytic b-GlcNAcase. Among them, NGT was the only one specifically designed to be an analog of the oxazolinium reaction intermediate based on the substrate-assisted mechanism, an attractive starting point to develop potent inhibitors. It is a major building block for the synthesis of potential inhibitors of transglycosylases involved in bacterial cell wall biosynthesis.
Status:
Possibly Marketed Outside US
Source:
CIS-MDP by Schwarzenbach, G.|Zurc, J.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Medronic acid (conjugate base, medronate) is a diagnostic agent that is used in complex with technetium Tc-99m for imaging delineate areas of altered osteogenesis. Upon administration the complex binds to hydroxyapatite crystals in bone.