SPISULOSINE

CCCCCCCCCCCCCCC[C@@H](O)[C@H](C)N

InChIKey=YRYJJIXWWQLGGV-ZWKOTPCHSA-N

InChI=1S/C18H39NO/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20)17(2)19/h17-18,20H,3-16,19H2,1-2H3/t17-,18+/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

PubMed

Title	Date	PubMed
Development and validation of a liquid chromatography-ultraviolet absorbance detection assay using derivatisation for the novel marine anticancer agent ES-285 x HCl [(2S,3R)-2-amino-3-octadecanol hydrochloride] and its pharmaceutical dosage form.	2003 Dec 12	14661748
Phenylisothiocyanate and dansyl chloride precolumn derivatizations for the high-performance liquid chromatography analysis of the antitumoral agent ES-285 in dog plasma.	2003 Jul 5	12798159
Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols.	2008 Aug	18499644
Phase I safety, pharmacokinetic, and pharmacogenomic trial of ES-285, a novel marine cytotoxic agent, administered to adult patients with advanced solid tumors.	2009 Jun	19509256
Deoxysphingoid bases as plasma markers in diabetes mellitus.	2010 Aug 16	20712864

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:04:48 GMT 2023` Edited by `admin` on `Sat Dec 16 08:04:48 GMT 2023`
Record UNII	ZX5D253CYY
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

SPISULOSINE

Common Name

English

3-OCTADECANOL, 2-AMINO-, (R-(R*,S*))-

Systematic Name

English

(+)-SPISULOSINE

Common Name

English

Spisulosine [WHO-DD]

Common Name

English

SPISULOSINE 285

Common Name

English

ES-285

Code

English

1-DEOXYSPHINGANINE

Systematic Name

English

3-OCTADECANOL, 2-AMINO-, (2S,3R)-

Systematic Name

English

Code System Code Type Description

SMS_ID

100000175281