Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C10H14N2O6 |
| Molecular Weight | 258.228 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=O)NC1=O
InChI
InChIKey=DWRXFEITVBNRMK-JXOAFFINSA-N
InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
| Molecular Formula | C10H14N2O6 |
| Molecular Weight | 258.228 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Specificity of anti-nucleoside antibodies in systemic lupus erythematosus. | 1983 Jun |
|
| Characterization of mouse and human monoclonal antibodies cross-reactive with SLE serum antibodies to guanosine. | 1984 Jun |
|
| Purification and characterization of uridine and thymidine phosphorylase from Lactobacillus casei. | 1990 Sep 3 |
|
| Enhanced high density oligonucleotide array-based sequence analysis using modified nucleoside triphosphates. | 1998 Nov 1 |
|
| Isolation and identification of apoptosis inducing nucleosides from CD57(+)HLA-DRbright natural suppressor cell line. | 1998 Oct 20 |
|
| Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells. | 2001 Nov |
|
| Dual function of the tRNA(m(5)U54)methyltransferase in tRNA maturation. | 2002 Mar |
|
| Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli. | 2002 Mar 15 |
|
| Three modifications in the D and T arms of tRNA influence translation in Escherichia coli and expression of virulence genes in Shigella flexneri. | 2002 Oct |
|
| Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase. | 2003 Sep 15 |
|
| Kilo-scale synthesis process for 2'-O-(2-methoxyethyl)-pyrimidine derivatives. | 2005 |
|
| Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system. | 2005 Mar 1 |
|
| 3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods. | 2006 Feb 15 |
|
| Temperature-dependent biosynthesis of 2-thioribothymidine of Thermus thermophilus tRNA. | 2006 Jan 27 |
|
| A counterintuitive Mg2+-dependent and modification-assisted functional folding of mitochondrial tRNAs. | 2006 Sep 29 |
|
| Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling. | 2007 Nov 29 |
|
| Selenium derivatization of nucleic acids for phase and structure determination in nucleic acid X-ray crystallography. | 2008 Mar |
|
| Crystallization and preliminary X-ray crystallographic characterization of TrmFO, a folate-dependent tRNA methyltransferase from Thermotoga maritima. | 2008 Mar 1 |
|
| Molecularly imprinted polymer of 5-methyluridine for solid-phase extraction of pyrimidine nucleoside cancer markers in urine. | 2008 Oct 1 |
|
| A study on the interaction between 5-Methyluridine and human serum albumin using fluorescence quenching method and molecular modeling. | 2010 Feb |
|
| Mutagenesis of the modified bases, m(5)U1939 and psi2504, in Escherichia coli 23S rRNA. | 2010 Feb 5 |
|
| Stereochemical mechanisms of tRNA methyltransferases. | 2010 Jan 21 |
|
| Differential effects of nucleotide analogs on scanning-dependent initiation and elongation of mammalian mRNA translation in vitro. | 2010 Jun |
|
| Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells. | 2010 May |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:30:15 GMT 2023
by
admin
on
Sat Dec 16 08:30:15 GMT 2023
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| Record UNII |
ZS1409014A
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| Record Status |
Validated (UNII)
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| Record Version |
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SUB197049
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m11839
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5-Methyluridine
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45996
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DTXSID20163348
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100000182769
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ZS1409014A
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215-973-9
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1463-10-1
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445408
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