EFLEPEDOCOKIN ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 03:43:55 GMT 2025` Edited by `admin` on `Wed Apr 02 03:43:55 GMT 2025`
Protein Type	FC FUSION PROTEIN
Protein Sub Type	INTERLEUKINS
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	ZQ9E6EX2JE
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

EFLEPEDOCOKIN ALFA

Official Name

English

F-652

Preferred Name

English

PROMENAKIN

Common Name

English

RECOMBINANT HUMAN INTERLEUKIN-22 IGG2-FC

Common Name

English

IL-22 DIMER F-652

Common Name

English

F-652 (RECOMBINANT FUSION PROTEIN CONSISTING OF TWO HUMAN INTERLEUKIN-22 (IL-22) MOLECULES LINKED TO AN IMMUNOGLOBULIN CONSTANT REGION (IGG2-FC))

Common Name

English

eflepedocokin alfa [INN]

Common Name

English

F 652 [WHO-DD]

Common Name

English

F652

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C26170

Created by admin on Wed Apr 02 03:43:55 GMT 2025 , Edited by admin on Wed Apr 02 03:43:55 GMT 2025

FDA ORPHAN DRUG

581117

Created by admin on Wed Apr 02 03:43:55 GMT 2025 , Edited by admin on Wed Apr 02 03:43:55 GMT 2025

Code System Code Type Description

INN

11233

Created by admin on Wed Apr 02 03:43:55 GMT 2025 , Edited by admin on Wed Apr 02 03:43:55 GMT 2025

PRIMARY

NCI_THESAURUS

C141419

Created by admin on Wed Apr 02 03:43:55 GMT 2025 , Edited by admin on Wed Apr 02 03:43:55 GMT 2025

PRIMARY

CAS

2200269-84-5

Created by admin on Wed Apr 02 03:43:55 GMT 2025 , Edited by admin on Wed Apr 02 03:43:55 GMT 2025

PRIMARY

CAS

1966971-51-6

Created by admin on Wed Apr 02 03:43:55 GMT 2025 , Edited by admin on Wed Apr 02 03:43:55 GMT 2025

NO STRUCTURE GIVEN

SMS_ID

300000019951

Created by admin on Wed Apr 02 03:43:55 GMT 2025 , Edited by admin on Wed Apr 02 03:43:55 GMT 2025

PRIMARY

FDA UNII

ZQ9E6EX2JE

Created by admin on Wed Apr 02 03:43:55 GMT 2025 , Edited by admin on Wed Apr 02 03:43:55 GMT 2025

PRIMARY

From	To
1_7	1_99
1_56	1_145
1_165	2_165
1_168	2_168
1_199	1_259
1_305	1_363
2_7	2_99
2_56	2_145
2_199	2_259
2_305	2_363

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_21
N	1_35
N	1_64
N	1_235
N	2_21
N	2_35
N	2_64
N	2_235

Related Record Type Details


					6TOW94RUK1

TARGET -> AGONIST

Amount:

Related Record Type Details


					ZQ9E6EX2JE

EFLEPEDOCOKIN ALFA

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_385] [2_385]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL