FLUTONIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H12FN3
Molecular Weight	193.2208
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CC=C(F)C=C1NC2=NCCN2

InChI

InChIKey=UYIZEUBMWCOJFF-UHFFFAOYSA-N

InChI=1S/C10H12FN3/c1-7-2-3-8(11)6-9(7)14-10-12-4-5-13-10/h2-3,6H,4-5H2,1H3,(H2,12,13,14)

HIDE SMILES / InChI

Molecular Formula	C10H12FN3
Molecular Weight	193.2208
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8103597 | https://www.ncbi.nlm.nih.gov/pubmed/6406947

Flutonidine, an alpha2-adrenergic receptor agonist was studied as an antihypertensive drug. However, information about the current use of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Effect of flutonidine on ouabain-induced arrhythmias and lethality in guinea-pig.	1993-05-01	8103597
Diuretic effects of flutonidine, a newer clonidine analog.	1987-01	3610239
[Long-term treatment with a new antihypertensive drug: flutonidin].	1983-05-19	6406947
alpha-Adrenoceptor activity of flutonidine (ST 600) in rat anococcygeus muscle and rabbit jejunum.	1982-04	6124607
A comparative trial of timolol and flutonidin as antihypertensive agents.	1982-02	7037661

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:08:46 GMT 2025` Edited by `admin` on `Mon Mar 31 18:08:46 GMT 2025`
Record UNII	ZCC19F3X8K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLUTONIDINE

Official Name

English

ST-600

Preferred Name

English

2-(5-FLUORO-O-TOLUIDINO)-2-IMIDAZOLINE

Common Name

English

flutonidine [INN]

Common Name

English

ST 600

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29709