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Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 13:31:13 GMT 2023
Edited
by admin
on Sat Dec 16 13:31:13 GMT 2023
Protein Type BISPECIFIC ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
ZAM5J1ATF2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CIBISATAMAB
INN   USAN  
Official Name English
ANTI-CEA/CD3 BISPECIFIC ANTIBODY RO6958688
Common Name English
HUMANIZED IMMUNOGLOBULIN G1 (IGG1) T-CELL BISPECIFIC (TCB) ANTIBODY TARGETING CARCINOEMBRYONIC ANTIGEN (CEA) AND CD3 EPSILON CHAIN (CD3E) ON T-CELLS
Common Name English
IMMUNOGLOBULIN G1-KAPPA/LAMBDA WITH DOMAIN CROSSOVER, ANTI-(HOMO SAPIENS CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 5 (CD66E ANTIGEN)) AND ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN (CD3E ANTIGEN)) HUMANIZED MONOCLONAL
Systematic Name English
RO6958688
Code English
CEA CD3 TCB
Common Name English
CIBISATAMAB [USAN]
Common Name English
RO-6958688
Code English
RG7802
Code English
cibisatamab [INN]
Common Name English
IMMUNOGLOBULIN G1, HUMANIZED BISPECIFIC TRIVALENT, ANTI-(HUMAN CARCINOEMBRYONIC ANTIGEN/HUMAN CD3 ANTIGEN .EPSILON.-CHAIN) BIVALENT .GAMMA.-CHAIN, DISULFIDE WITH ANTI-(HUMAN CARCINOEMBRYONIC ANTIGEN) .KAPPA.-CHAIN, ANTI-(HUMAN CARCINOEMBRYONIC ANTIGEN) M
Systematic Name English
Cibisatamab [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C129822
Created by admin on Sat Dec 16 13:31:13 GMT 2023 , Edited by admin on Sat Dec 16 13:31:13 GMT 2023
NCI_THESAURUS C28227
Created by admin on Sat Dec 16 13:31:13 GMT 2023 , Edited by admin on Sat Dec 16 13:31:13 GMT 2023
FDA ORPHAN DRUG 618817
Created by admin on Sat Dec 16 13:31:13 GMT 2023 , Edited by admin on Sat Dec 16 13:31:13 GMT 2023
Code System Code Type Description
CAS
2101242-53-7
Created by admin on Sat Dec 16 13:31:13 GMT 2023 , Edited by admin on Sat Dec 16 13:31:13 GMT 2023
PRIMARY
USAN
FG-176
Created by admin on Sat Dec 16 13:31:13 GMT 2023 , Edited by admin on Sat Dec 16 13:31:13 GMT 2023
PRIMARY
CAS
1855925-27-7
Created by admin on Sat Dec 16 13:31:13 GMT 2023 , Edited by admin on Sat Dec 16 13:31:13 GMT 2023
ALTERNATIVE
INN
10636
Created by admin on Sat Dec 16 13:31:13 GMT 2023 , Edited by admin on Sat Dec 16 13:31:13 GMT 2023
PRIMARY
FDA UNII
ZAM5J1ATF2
Created by admin on Sat Dec 16 13:31:13 GMT 2023 , Edited by admin on Sat Dec 16 13:31:13 GMT 2023
PRIMARY
NCI_THESAURUS
C120097
Created by admin on Sat Dec 16 13:31:13 GMT 2023 , Edited by admin on Sat Dec 16 13:31:13 GMT 2023
PRIMARY
From To
1_22 1_96
1_148 1_204
1_257 1_333
1_387 1_447
1_508 1_568
1_614 1_672
5_22 5_90
2_22 2_96
3_23 3_88
4_23 4_88
3_135 3_195
4_135 4_195
5_138 5_194
2_148 2_204
1_467 5_214
1_224 3_215
2_224 4_215
1_473 2_230
1_476 2_233
2_265 2_325
1_601 2_353
2_371 2_429
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_544
N 2_301
Related Record Type Details
T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN
TARGET -> ACTIVATOR
Related Record Type Details
CIBISATAMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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