PIPETHANATE ETHOBROMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H30NO3.Br
Molecular Weight	448.393
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Br-].CC[N+]3(CCOC(=O)C(O)(C1=CC=CC=C1)C2=CC=CC=C2)CCCCC3

InChI

InChIKey=VPUGSHLBERYQGC-UHFFFAOYSA-M

InChI=1S/C23H30NO3.BrH/c1-2-24(16-10-5-11-17-24)18-19-27-22(25)23(26,20-12-6-3-7-13-20)21-14-8-4-9-15-21;/h3-4,6-9,12-15,26H,2,5,10-11,16-19H2,1H3;1H/q+1;/p-1

HIDE SMILES / InChI

Molecular Formula	C23H29NO3
Molecular Weight	367.4813
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.druginfosys.com/drug.aspx?drugcode=2164&type=1
Curator's Comment: description was created based on several sources, including https://www.drugs.com/international/pipethanate-ethobromide.html | http://www.druginfosys.com/drug.aspx?drugcode=2164&type=1 | https://www.ncbi.nlm.nih.gov/pubmed/5170094 | http://www.rjbc.ru/arc/11/10/1402-1416.pdf | https://www.ncbi.nlm.nih.gov/pubmed/5170093

Pipethanate ethobromide is an antimuscarinic with actions similar to those of atropine. It has been used in the symptomatic treatment of visceral spasms in oral doses of up to 160 mg daily in divided doses. Pipethanate ethobromide has also been given intramuscularly or intravenously in doses of 10 to 20 mg daily and rectally in doses of 60 or 120 mg daily.

CNS Activity

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Muscarinic acetylcholine receptor 160 Target ID: CHEMBL2094109 Sources: http://www.rjbc.ru/arc/11/10/1402-1416.pdf	Antagonist 2778

Conditions

Condition	Modality	Targets	Highest Phase	Product
Gastritis 45 Sources: http://www.druginfosys.com/drug.aspx?drugcode=2164&type=1	Primary		Approved 8429	Epithanate G Approved Use Unknown

PubMed

Title	Date	PubMed
Determination of diphenylmethane antihistaminic drugs and their analogues in body fluids by gas chromatography with surface ionization detection.	1992 Oct 23	1360473

Patents

Sample Use Guides

In Vivo Use Guide

up to 160 mg daily in divided doses

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 07:15:27 GMT 2023` Edited by `admin` on `Sat Dec 16 07:15:27 GMT 2023`
Record UNII	ZA38L5WD1K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PIPETHANATE ETHOBROMIDE

Common Name

English

PIPETHANATE ETHOBROMIDE [JAN]

Common Name

English

Pipethanate ethobromide [WHO-DD]

Common Name

English

1-ETHYL-1-(2-((HYDROXY(DIPHENYL)ACETYL)OXY)ETHYL)PIPERIDINIUM BROMIDE

Systematic Name

English

PIPERILATE ETHYL BROMIDE

Common Name

English

PIPERILATE ETHYL BROMIDE [MI]

Common Name

English

PANPUROL

Brand Name

English

Code System Code Type Description

FDA UNII

ZA38L5WD1K