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Details

Stereochemistry ABSOLUTE
Molecular Formula C45H74O17
Molecular Weight 887.0589
Optical Activity UNSPECIFIED
Defined Stereocenters 27 / 27
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ASPARANIN B

SMILES

C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@@H]5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]6O[C@H](CO)[C@@H](O[C@@H]7O[C@@H](C)[C@H](O)[C@@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)O[C@]19CC[C@H](C)CO9

InChI

InChIKey=BCUDKRWNGQAFLF-PJFZGHSASA-N
InChI=1S/C45H74O17/c1-19-8-13-45(55-18-19)20(2)30-27(62-45)15-26-24-7-6-22-14-23(9-11-43(22,4)25(24)10-12-44(26,30)5)57-42-39(61-41-36(53)34(51)32(49)28(16-46)58-41)37(54)38(29(17-47)59-42)60-40-35(52)33(50)31(48)21(3)56-40/h19-42,46-54H,6-18H2,1-5H3/t19-,20-,21-,22+,23-,24+,25-,26-,27-,28+,29+,30-,31-,32+,33+,34-,35+,36+,37-,38+,39+,40-,41-,42+,43-,44-,45+/m0/s1

HIDE SMILES / InChI
Molecular Formula C45H74O17
Molecular Weight 887.0589
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 27 / 27
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Asparanin B is a steroidal saponin from the roots of Asparagus racemosus. It has being shown to exhibit significant anticancer activity in both in vitro and in vivo experimental models.

Approval Year

Unknown
149124
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8504
Inhibitor
8504
A498
1
Target ID: CHEMBL614516
Inhibitor
8504
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Basic research
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Shatavarins (containing Shatavarin IV) with anticancer activity from the roots of Asparagus racemosus.
2011-08-16
Steroidal saponins from the roots of Asparagus racemosus.
2008-02
Patents

Patents

US20150125435
1

Sample Use Guides

In Vivo Use Guide
250 and 500 mg/kg b.wt., orally, once daily for 10 days
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:47:41 GMT 2025
Edited
by admin
on Mon Mar 31 21:47:41 GMT 2025
Record UNII
Z905922Y1P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CURILLIN H
Preferred Name English
ASPARANIN B
Common Name English
.BETA.-D-GLUCOPYRANOSIDE, (3.BETA.,5.BETA.,25S)-SPIROSTAN-3-YL O-6-DEOXY-.ALPHA.-L-MANNOPYRANOSYL-(1->4)-O-(.BETA.-D-GLUCOPYRANOSYL-(1->2))-
Systematic Name English
SHATAVARIN IV
Common Name English
Code System Code Type Description
CAS
84633-34-1
Created by admin on Mon Mar 31 21:47:41 GMT 2025 , Edited by admin on Mon Mar 31 21:47:41 GMT 2025
PRIMARY
PUBCHEM
441896
Created by admin on Mon Mar 31 21:47:41 GMT 2025 , Edited by admin on Mon Mar 31 21:47:41 GMT 2025
PRIMARY
FDA UNII
Z905922Y1P
Created by admin on Mon Mar 31 21:47:41 GMT 2025 , Edited by admin on Mon Mar 31 21:47:41 GMT 2025
PRIMARY
EPA CompTox
DTXSID501317487
Created by admin on Mon Mar 31 21:47:41 GMT 2025 , Edited by admin on Mon Mar 31 21:47:41 GMT 2025
PRIMARY
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NIH
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