Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H13Cl2N5O2 |
| Molecular Weight | 426.256 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=CC=C2C(COC3=CC=C(Cl)C(OC4=CC(=CC(Cl)=C4)C#N)=C3)=NNC2=N1
InChI
InChIKey=KXDIHAQCVNNLIB-UHFFFAOYSA-N
InChI=1S/C20H13Cl2N5O2/c21-12-5-11(9-23)6-14(7-12)29-18-8-13(1-3-16(18)22)28-10-17-15-2-4-19(24)25-20(15)27-26-17/h1-8H,10H2,(H3,24,25,26,27)
| Molecular Formula | C20H13Cl2N5O2 |
| Molecular Weight | 426.256 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Design and synthesis of conformationally constrained inhibitors of non-nucleoside reverse transcriptase. | 2011-11-24 |
|
| Looking for an active conformation of the future HIV type-1 non-nucleoside reverse transcriptase inhibitors. | 2010-08-11 |
|
| Antiviral activity of MK-4965, a novel nonnucleoside reverse transcriptase inhibitor. | 2009-06 |
|
| Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): a potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses. | 2008-10-23 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:04:49 GMT 2025
by
admin
on
Mon Mar 31 21:04:49 GMT 2025
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| Record UNII |
Z8856WDK9S
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| Record Status |
Validated (UNII)
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| Record Version |
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