Details
Stereochemistry | RACEMIC |
Molecular Formula | C8H12N2 |
Molecular Weight | 136.1943 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(NN)C1=CC=CC=C1
InChI
InChIKey=HHRZAEJMHSGZNP-UHFFFAOYSA-N
InChI=1S/C8H12N2/c1-7(10-9)8-5-3-2-4-6-8/h2-7,10H,9H2,1H3
Molecular Formula | C8H12N2 |
Molecular Weight | 136.1943 |
Charge | 0 |
Count |
|
Stereochemistry | RACEMIC |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Optical Activity | ( + / - ) |
Mebanazine is an inhibitor of monoamine oxidase. It was introduced in the 1960s for the treatment of depression and was marketed under trade name Actomol. The drug was withdrawn from the market due to hepatotoxicity. In addition to its antidepressant effect, the drug was found to possess an anorexic action and in animal models, it potentiated the hypoglycemic response to insulin and delayed the recovery of blood glucose levels to normal.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL2095205 Sources: https://www.ncbi.nlm.nih.gov/pubmed/5889715 |
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 17:52:27 GMT 2023
by
admin
on
Sat Dec 16 17:52:27 GMT 2023
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Record UNII |
Z5R55CJ4CG
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Record Status |
Validated (UNII)
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Record Version |
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C667
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admin on Sat Dec 16 17:52:27 GMT 2023 , Edited by admin on Sat Dec 16 17:52:27 GMT 2023
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CHEMBL1909283
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1722
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200-615-6
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100000081729
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C80969
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SUB08659MIG
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C004343
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DB09248
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6179
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Z5R55CJ4CG
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65-64-5
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4865
Created by
admin on Sat Dec 16 17:52:27 GMT 2023 , Edited by admin on Sat Dec 16 17:52:27 GMT 2023
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Mebanazine
Created by
admin on Sat Dec 16 17:52:27 GMT 2023 , Edited by admin on Sat Dec 16 17:52:27 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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ACTIVE MOIETY |