U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C25H24F2N4OS
Molecular Weight 466.546
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NRA-0562

SMILES

NC(=O)C1=NC(=C(CCN2CCC(CC2)C3=CNC4=C3C=CC(F)=C4)S1)C5=CC=C(F)C=C5

InChI

InChIKey=KGCLWPBGLDFQHP-UHFFFAOYSA-N
InChI=1S/C25H24F2N4OS/c26-17-3-1-16(2-4-17)23-22(33-25(30-23)24(28)32)9-12-31-10-7-15(8-11-31)20-14-29-21-13-18(27)5-6-19(20)21/h1-6,13-15,29H,7-12H2,(H2,28,32)

HIDE SMILES / InChI

Molecular Formula C25H24F2N4OS
Molecular Weight 466.546
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Neuropharmacological profiles of a novel atypical antipsychotic, NRA0562, in rats.
2001 Jun 29
In vitro and in vivo pharmacological profile of 5-[2-[4-(6-fluoro-1H-indole-3-yl)piperidin-1-yl]ethyl]-4-(4-fluorophenyl)thiazole-2-carboxylic acid amide (NRA0562), a novel and putative atypical antipsychotic.
2002 Aug 9
Antipsychotic profile of 5-[2-[4-(6-fluoro-1H-indole-3-yl)piperidin-1-yl]ethyl]-4-(4-fluorophenyl)thiazole-2-carboxylic acid amide (NRA0562) in rats.
2002 Jul 12
Antipsychotic action of selective group II metabotropic glutamate receptor agonist MGS0008 and MGS0028 on conditioned avoidance responses in the rat.
2003 Aug 15
Substance Class Chemical
Created
by admin
on Sat Dec 16 09:44:35 GMT 2023
Edited
by admin
on Sat Dec 16 09:44:35 GMT 2023
Record UNII
Z2684U429S
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NRA-0562
Common Name English
2-THIAZOLECARBOXAMIDE, 5-(2-(4-(6-FLUORO-1H-INDOL-3-YL)-1-PIPERIDINYL)ETHYL)-4-(4-FLUOROPHENYL)-
Systematic Name English
Code System Code Type Description
CAS
244276-65-1
Created by admin on Sat Dec 16 09:44:35 GMT 2023 , Edited by admin on Sat Dec 16 09:44:35 GMT 2023
PRIMARY
PUBCHEM
9804574
Created by admin on Sat Dec 16 09:44:35 GMT 2023 , Edited by admin on Sat Dec 16 09:44:35 GMT 2023
PRIMARY
FDA UNII
Z2684U429S
Created by admin on Sat Dec 16 09:44:35 GMT 2023 , Edited by admin on Sat Dec 16 09:44:35 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY