U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 18:41:56 GMT 2023
Edited
by admin
on Sat Dec 16 18:41:56 GMT 2023
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE ATTENUATED GENETICALLY MODIFIED
Organism Family Adenoviridae
Organism Genus Mastadenovirus
Organism Species human mastadenovirus c
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name Ad5-l promoter of E1A replaced with (TERT)-ΔE1B-19k- human relaxin 1 gen
Part whole
Record UNII
YZP73R8LDT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OPILRELAGENE ATRADENOREPVEC
INN  
Official Name English
DNA (RECOMBINANT HUMAN ADENOVIRUS 5 .DELTA.E1B-19K ONCOLYTIC VECTOR GM101 HUMAN MODIFIED TELOMERASE PROMOTER PLUS HUMAN RELAXIN 1 PRECURSOR-SPECIFYING)
Common Name English
opilrelagene atradenorepvec [INN]
Common Name English
RECOMBINANT REPLICATION-COMPETENT ONCOLYTIC ADENOVIRUS TYPE 5 (AD5), WITH THE ORIGINAL PROMOTER OF E1A REPLACED WITH TWO CONSECUTIVE HUMAN TELOMERASE REVERSE TRANSCRIPTASE (TERT) PROMOTERS, WITH E1B-19KDA INACTIVATED (BY DELETION OF THE START CODON AND T
Common Name English
Code System Code Type Description
CAS
2413849-94-0
Created by admin on Sat Dec 16 18:41:56 GMT 2023 , Edited by admin on Sat Dec 16 18:41:56 GMT 2023
PRIMARY
NCI_THESAURUS
C188665
Created by admin on Sat Dec 16 18:41:56 GMT 2023 , Edited by admin on Sat Dec 16 18:41:56 GMT 2023
PRIMARY
FDA UNII
YZP73R8LDT
Created by admin on Sat Dec 16 18:41:56 GMT 2023 , Edited by admin on Sat Dec 16 18:41:56 GMT 2023
PRIMARY
INN
11696
Created by admin on Sat Dec 16 18:41:56 GMT 2023 , Edited by admin on Sat Dec 16 18:41:56 GMT 2023
PRIMARY
Related Record Type Details
EXPRESSED PROTEIN->VECTOR
EXPRESSED PROTEIN->VECTOR
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
INSERTED GENE EXPRESSION VECTOR OPILRELAGENE ATRADENOREPVEC TRANSGENE INSERT 255AZD28HP