SULFAPROXYLINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H18N2O4S
Molecular Weight	334.39
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)OC1=CC=C(C=C1)C(=O)NS(=O)(=O)C2=CC=C(N)C=C2

InChI

InChIKey=FBFBRAFXKGRRHI-UHFFFAOYSA-N

InChI=1S/C16H18N2O4S/c1-11(2)22-14-7-3-12(4-8-14)16(19)18-23(20,21)15-9-5-13(17)6-10-15/h3-11H,17H2,1-2H3,(H,18,19)

HIDE SMILES / InChI

Molecular Formula	C16H18N2O4S
Molecular Weight	334.39
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13473126 | https://www.ncbi.nlm.nih.gov/pubmed/13946335 | https://www.ncbi.nlm.nih.gov/pubmed/5330705

Sulfaproxyline is a sulfonamide derivative patented by J. R. Geigy A.-G. as an antibiotic, useful in the treatment of urinary tract infections. In preclinical models, sulfaproxyline is effective against staphylococci infection in guinea pigs. Bisulfon D, a drug product comprising the combination of sulfaproxyline and sulfamerazine has been used for the treatment of urinary tract infections in the puerperium.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Synergism of action of sulfamerazine and sulfaproxyline in an experimental staphylococcic infection in guinea pigs].	1957 May	13473126

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:51:05 GMT 2023` Edited by `admin` on `Fri Dec 15 15:51:05 GMT 2023`
Record UNII	YR841R53VW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SULFAPROXYLINE

Official Name

English

SULFAPROXYLINE [MI]

Common Name

English

NSC-120646

Code

English

sulfaproxyline [INN]

Common Name

English

Sulfaproxyline [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C255