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Details

Stereochemistry ACHIRAL
Molecular Formula C14H18N2O2
Molecular Weight 246.3049
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PARSALMIDE

SMILES

CCCCNC(=O)C1=C(OCC#C)C=CC(N)=C1

InChI

InChIKey=DXHYQIJBUNRPJT-UHFFFAOYSA-N
InChI=1S/C14H18N2O2/c1-3-5-8-16-14(17)12-10-11(15)6-7-13(12)18-9-4-2/h2,6-7,10H,3,5,8-9,15H2,1H3,(H,16,17)

HIDE SMILES / InChI
Molecular Formula C14H18N2O2
Molecular Weight 246.3049
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

PARSALMIDE, a benzamide derivative, is an anti-inflammatory drug with analgesic effect. It may also possess anxiolytic and tranquilizing properties. PARSALMIDE was commercialized in Italy until 1985 with the brand name of Synovial®, that was widely used to treat arthritic patients.

Approval Year

Unknown
149,124

PubMed

Patents

20020037524
7
JP2002516087A
1

Sample Use Guides

In Vitro Use Guide
Parsalmide inhibited purified ovine COX-1 and COX-2 in vitro with IC50 9.92 uM 155 uM, respectively.
Substance Class Chemical
Record UNII
YQH5093J7C
Record Status Validated (UNII)
Record Version
NIH
NCATS
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