N-(2-(METHYLAMINO)ETHYL)ISOQUINOLINE-5-SULFONAMIDE HYDROCHLORIDE

Cl.CNCCNS(=O)(=O)C1=CC=CC2=CN=CC=C12

InChIKey=WGYFLDSVYRDHDI-UHFFFAOYSA-N

InChI=1S/C12H15N3O2S.ClH/c1-13-7-8-15-18(16,17)12-4-2-3-10-9-14-6-5-11(10)12;/h2-6,9,13,15H,7-8H2,1H3;1H

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Protein kinase C (PKC) 44 Target ID: CHEMBL2094266 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2161662	Inhibitor 8504	36.0 µM [IC50]
G-protein coupled receptor kinase 2 2 Target ID: CHEMBL4079 Sources: https://www.ncbi.nlm.nih.gov/pubmed/11741218	Inhibitor 8504	100.0 µM [IC50]
Protein kinase C (PKC) 44 Target ID: CHEMBL2093867 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8824261	Inhibitor 8504	15.0 µM [Ki]

Substance Class	Chemical Created by `admin` on `Wed Apr 02 11:09:48 GMT 2025` Edited by `admin` on `Wed Apr 02 11:09:48 GMT 2025`
Record UNII	YPR5E3J77X
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

5-ISOQUINOLINESULFONAMIDE, N-(2-(METHYLAMINO)ETHYL)-, MONOHYDROCHLORIDE

Preferred Name

English

N-(2-(METHYLAMINO)ETHYL)ISOQUINOLINE-5-SULFONAMIDE HYDROCHLORIDE

Systematic Name

English

Code System Code Type Description

PUBCHEM

9904471

Created by admin on Wed Apr 02 11:09:48 GMT 2025 , Edited by admin on Wed Apr 02 11:09:48 GMT 2025

PRIMARY

CAS

116970-62-8

Created by admin on Wed Apr 02 11:09:48 GMT 2025 , Edited by admin on Wed Apr 02 11:09:48 GMT 2025

PRIMARY

FDA UNII

YPR5E3J77X

Created by admin on Wed Apr 02 11:09:48 GMT 2025 , Edited by admin on Wed Apr 02 11:09:48 GMT 2025

PRIMARY

Related Record Type Details


					TX277E49WT

PARENT -> SALT/SOLVATE

Amount: