N-(2-(METHYLAMINO)ETHYL)ISOQUINOLINE-5-SULFONAMIDE

CNCCNS(=O)(=O)C1=CC=CC2=C1C=CN=C2

InChIKey=PJWUXKNZVMEPPH-UHFFFAOYSA-N

InChI=1S/C12H15N3O2S/c1-13-7-8-15-18(16,17)12-4-2-3-10-9-14-6-5-11(10)12/h2-6,9,13,15H,7-8H2,1H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Protein kinase C (PKC) 44 Target ID: CHEMBL2094266 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2161662	Inhibitor 8297	36.0 µM [IC50]
G-protein coupled receptor kinase 2 2 Target ID: CHEMBL4079 Sources: https://www.ncbi.nlm.nih.gov/pubmed/11741218	Inhibitor 8297	100.0 µM [IC50]
Protein kinase C (PKC) 44 Target ID: CHEMBL2093867 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8824261	Inhibitor 8297	15.0 µM [Ki]

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:38:44 GMT 2023` Edited by `admin` on `Fri Dec 15 19:38:44 GMT 2023`
Record UNII	TX277E49WT
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

N-(2-(METHYLAMINO)ETHYL)ISOQUINOLINE-5-SULFONAMIDE

Common Name

English

H-8

Common Name

English

PROTEIN KINASE INHIBITOR H8

Common Name

English

5-ISOQUINOLINESULFONAMIDE, N-(2-(METHYLAMINO)ETHYL)-

Systematic Name

English

N-(2-(METHYLAMINO)ETHYL)-5-ISOQUINOLINESULFONAMIDE

Systematic Name

English

Code System Code Type Description

CAS

84478-11-5