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Details

Stereochemistry ACHIRAL
Molecular Formula C10H10N6O2
Molecular Weight 246.2254
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of AZANIDAZOLE

SMILES

CN1C(\C=C\C2=NC(N)=NC=C2)=NC=C1[N+]([O-])=O

InChI

InChIKey=LHIALLMPKJMSIQ-NSCUHMNNSA-N
InChI=1S/C10H10N6O2/c1-15-8(13-6-9(15)16(17)18)3-2-7-4-5-12-10(11)14-7/h2-6H,1H3,(H2,11,12,14)/b3-2+

HIDE SMILES / InChI
Molecular Formula C10H10N6O2
Molecular Weight 246.2254
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Description

Azanidazole (or Triclose), an antitrichomonal agent that is used to treat the vaginal trichomoniasis in Italy. This drug causes genotoxicity in liver and kidney that is not separated from its biological activity.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Combined systemic and topical treatment of trichomoniasis vaginalis with azanidazol.
1981
Mutagenicity of a series of 25 nitroimidazoles and two nitrothiazoles in Salmonella typhimurium.
1983
[Clinical results of the treatment of vaginal trichomoniasis with azanidazole].
1983 Jan-Feb
The organospecific activity of metronidazole and azanidazole in the intrasanguineous host-mediated assay.
1985
In vivo protective role of antioxidants against genotoxicity of metronidazole and azanidazole.
1987
Substance Class Chemical
Created
by admin
on Sat Dec 16 18:00:55 UTC 2023
Edited
by admin
on Sat Dec 16 18:00:55 UTC 2023
Record UNII
YP2Y0DRX4S
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AZANIDAZOLE
INN   MART.   MI   USAN   WHO-DD  
USAN   INN  
Official Name English
2-PYRIMIDINAMINE, 4-(2-(1-METHYL-5-NITRO-1H-IMIDAZOL-2-YL)ETHENYL)-, (E)-
Common Name English
azanidazole [INN]
Common Name English
Azanidazole [WHO-DD]
Common Name English
AZANIDAZOLE [MART.]
Common Name English
AZANIDAZOLE [MI]
Common Name English
(E)-2-Amino-4-[2-(1-methyl-5-nitroimidazol-2-yl)vinyl]pyrimidine
Systematic Name English
AZANIDAZOLE [USAN]
Common Name English
Classification Tree Code System Code
WHO-ATC G01AF13
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
NCI_THESAURUS C277
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
WHO-ATC P01AB04
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
WHO-VATC QG01AF13
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
WHO-VATC QP51AA04
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
Code System Code Type Description
MESH
C023624
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
SMS_ID
100000086891
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
WIKIPEDIA
AZANIDAZOLE
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
FDA UNII
YP2Y0DRX4S
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
MERCK INDEX
m2160
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY Merck Index
INN
4274
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
ChEMBL
CHEMBL134920
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
CAS
62973-76-6
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
PUBCHEM
6436171
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
NCI_THESAURUS
C73274
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
DRUG CENTRAL
264
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
EVMPD
SUB05635MIG
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
DRUG BANK
DB13350
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
EPA CompTox
DTXSID40212180
Created by admin on Sat Dec 16 18:00:55 UTC 2023 , Edited by admin on Sat Dec 16 18:00:55 UTC 2023
PRIMARY
Related Record Type Details
Structure of AZANIDAZOLE
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