AZANIDAZOLE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H10N6O2
Molecular Weight	246.2254
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1C(\C=C\C2=CC=NC(N)=N2)=NC=C1[N+]([O-])=O

InChI

InChIKey=LHIALLMPKJMSIQ-NSCUHMNNSA-N

InChI=1S/C10H10N6O2/c1-15-8(13-6-9(15)16(17)18)3-2-7-4-5-12-10(11)14-7/h2-6H,1H3,(H2,11,12,14)/b3-2+

HIDE SMILES / InChI

Molecular Formula	C10H10N6O2
Molecular Weight	246.2254
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3322753 | https://www.ncbi.nlm.nih.gov/pubmed/6682212 | https://www.ncbi.nlm.nih.gov/pubmed/6132457

Azanidazole (or Triclose), an antitrichomonal agent that is used to treat the vaginal trichomoniasis in Italy. This drug causes genotoxicity in liver and kidney that is not separated from its biological activity.

Approval Year

PubMed

Title	Date	PubMed
In vivo protective role of antioxidants against genotoxicity of metronidazole and azanidazole.	1987	3322753
The organospecific activity of metronidazole and azanidazole in the intrasanguineous host-mediated assay.	1985	3915465
[Clinical results of the treatment of vaginal trichomoniasis with azanidazole].	1983-01-01	6682212
Mutagenicity of a series of 25 nitroimidazoles and two nitrothiazoles in Salmonella typhimurium.	1983	6132457
Combined systemic and topical treatment of trichomoniasis vaginalis with azanidazol.	1981	7307267

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:56:00 GMT 2025` Edited by `admin` on `Wed Apr 02 09:56:00 GMT 2025`
Record UNII	YP2Y0DRX4S
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AZANIDAZOLE [MI]

Preferred Name

English

AZANIDAZOLE

Official Name

English

2-PYRIMIDINAMINE, 4-(2-(1-METHYL-5-NITRO-1H-IMIDAZOL-2-YL)ETHENYL)-, (E)-

Common Name

English

azanidazole [INN]

Common Name

English

Azanidazole [WHO-DD]

Common Name

English

AZANIDAZOLE [MART.]

Common Name

English

(E)-2-Amino-4-[2-(1-methyl-5-nitroimidazol-2-yl)vinyl]pyrimidine

Systematic Name

English

AZANIDAZOLE [USAN]

Common Name

English

Classification Tree Code System Code

WHO-ATC

G01AF13