AZANIDAZOLE

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H10N6O2
Molecular Weight	246.2254
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

SMILES

CN1C(\C=C\C2=NC(N)=NC=C2)=NC=C1[N+]([O-])=O

InChI

InChIKey=LHIALLMPKJMSIQ-NSCUHMNNSA-N

InChI=1S/C10H10N6O2/c1-15-8(13-6-9(15)16(17)18)3-2-7-4-5-12-10(11)14-7/h2-6H,1H3,(H2,11,12,14)/b3-2+

HIDE SMILES / InChI

Molecular Formula	C10H10N6O2
Molecular Weight	246.2254
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description

Azanidazole (or Triclose), an antitrichomonal agent that is used to treat the vaginal trichomoniasis in Italy. This drug causes genotoxicity in liver and kidney that is not separated from its biological activity.

Approval Year

PubMed

PubMed

Show entries

Title	Date	PubMed
Combined systemic and topical treatment of trichomoniasis vaginalis with azanidazol.	1981	7307267
Mutagenicity of a series of 25 nitroimidazoles and two nitrothiazoles in Salmonella typhimurium.	1983	6132457
[Clinical results of the treatment of vaginal trichomoniasis with azanidazole].	1983 Jan-Feb	6682212
The organospecific activity of metronidazole and azanidazole in the intrasanguineous host-mediated assay.	1985	3915465
In vivo protective role of antioxidants against genotoxicity of metronidazole and azanidazole.	1987	3322753