BENZOBARBITAL

Investigational

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H16N2O4
Molecular Weight	336.3413
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

CCC1(C(=O)NC(=O)N(C(=O)C2=CC=CC=C2)C1=O)C3=CC=CC=C3

InChI

InChIKey=QMOWPJIFTHVQMB-UHFFFAOYSA-N

InChI=1S/C19H16N2O4/c1-2-19(14-11-7-4-8-12-14)16(23)20-18(25)21(17(19)24)15(22)13-9-5-3-6-10-13/h3-12H,2H2,1H3,(H,20,23,25)

HIDE SMILES / InChI

Molecular Formula	C19H16N2O4
Molecular Weight	336.3413
Charge	0
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description

Benzobarbital (under the brand name Benzona), a barbiturate derivative developed in Russia that is used to treat convulsive forms of epilepsy, newborn hemolytic disease, and insomnia.

Approval Year

PubMed

PubMed

Show entries

Title	Date	PubMed
[Prospects of using hard dispersions in development of dosage forms for therapeutic and prophylactic use].	2001	11255953
[The liver monooxygenase system activity in the long-term compression syndrome and treatment with benzonal in prepubertal rats and rabbits].	2001 Mar-Apr	11548454
[The effect of Asian cobra venom on the content of rat heart and liver mitochondrial phospholipids and the protective effect of benzonal].	2005 Sep-Oct	16342667
[Analysis of blood hormone levels in boys of prepubertal and pubertal age with epilepsy treated with different antiepileptic drugs].	2008	19618713

Showing 1 to 4 of 4 entries

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Sample Use Guides

In Vivo Use Guide

For adults: 0.1 g 3 times a day (the highest daily dose is 0.8 g), for children (3 times a day): 3–6 years - 0.025–0.05 g, 7–10 years - 0, 05–0.1 g, 11–14 years old - 0.1 g (the highest daily is 0.45 g);

Route of Administration: Oral