NIDROXYZONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H10N4O5
Molecular Weight	242.1888
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of NIDROXYZONE

Structure Search

SMILES

NC(=O)N(CCO)\N=C\C1=CC=C(O1)[N+]([O-])=O

InChI

InChIKey=FJVAAURIDNIYAE-BJMVGYQFSA-N

InChI=1S/C8H10N4O5/c9-8(14)11(3-4-13)10-5-6-1-2-7(17-6)12(15)16/h1-2,5,13H,3-4H2,(H2,9,14)/b10-5+

HIDE SMILES / InChI

Molecular Formula	C8H10N4O5
Molecular Weight	242.1888
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15442384 | https://www.ncbi.nlm.nih.gov/pubmed/24542405 | https://www.drugfuture.com/chemdata/nidroxyzone.html

Nidroxyzone (Furadroxyl) is an antibacterial agent. It was used for the treatment of experimental trypanosomiasis in laboratory animals.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Antibacterial action of neomycin and furadroxyl in vitro and in vivo].	1950 Jun 26	15442384
The use of 5-nitro-2-furaldehyde-2(2-hydroxyethyl) semicarbazone (furadroxyl) in the treatment of experimental trypanosomiasis in laboratory animals.	1953 Apr	24542405
The effect of furadroxyl treatment and x-irradiation on the hyaluronidase concentration of rat testes.	1957 Jan	13384389

Patents

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:53:38 GMT 2023` Edited by `admin` on `Sat Dec 16 16:53:38 GMT 2023`
Record UNII	YN9DMN3CVQ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NIDROXYZONE

Official Name

English

nidroxyzone [INN]

Common Name

English

NSC-6474

Code

English

5-NITRO-2-FURALDEHYDE 2-(2-HYDROXYETHYL)SEMICARBAZONE

Systematic Name

English

NIDROXYZONE [MI]

Common Name

English

NITROFUROXIZONE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28394

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

Code System Code Type Description

ECHA (EC/EINECS)

206-970-3

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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NSC

6474

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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SMS_ID

100000084401

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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NCI_THESAURUS

C84014

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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INN

693

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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EVMPD

SUB09252MIG

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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CAS

405-22-1

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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DRUG CENTRAL

3794

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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FDA UNII

YN9DMN3CVQ

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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EPA CompTox

DTXSID701015578

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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PUBCHEM

9570072

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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ChEMBL

CHEMBL92444

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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MERCK INDEX

m366

Created by admin on Sat Dec 16 16:53:38 GMT 2023 , Edited by admin on Sat Dec 16 16:53:38 GMT 2023

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Merck Index

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					YN9DMN3CVQ

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