CX-659S

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C25H28N4O5
Molecular Weight	464.5136
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1C(=O)N(C2=CC=CC=C2)C(N)=C(NC(=O)[C@]3(C)CCC4=C(C)C(O)=C(C)C(C)=C4O3)C1=O

InChI

InChIKey=NOYZWUQUALADDO-VWLOTQADSA-N

InChI=1S/C25H28N4O5/c1-13-14(2)20-17(15(3)19(13)30)11-12-25(4,34-20)23(32)27-18-21(26)29(16-9-7-6-8-10-16)24(33)28(5)22(18)31/h6-10,30H,11-12,26H2,1-5H3,(H,27,32)/t25-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C25H28N4O5
Molecular Weight	464.5136
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Synthesis and activity of a metabolite of (S)-6-amino-5-(6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamido)-3-methyl-1-phenyl-2,4-(1H,3H)-pyrimidinedione (CX-659S).	2002 Oct	12372880
The combined effect of topical CX-659S, a novel diaminouracil derivative, with topical corticosteroid on the three types of allergic responses in mice or guinea pigs.	2003 Jan	12686733
Inhibitory activity of CX-659S, a novel diaminouracil derivative, against the rebound phenomenon following withdrawal of corticosteroid therapy for chronic contact hypersensitivity responses.	2003 Jun	12811023

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:34:34 GMT 2023` Edited by `admin` on `Sat Dec 16 09:34:34 GMT 2023`
Record UNII	YG2F04AVMQ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CX-659S

Common Name

English

2H-1-BENZOPYRAN-2-CARBOXAMIDE, N-(6-AMINO-1,2,3,4-TETRAHYDRO-3-METHYL-2,4-DIOXO-1-PHENYL-5-PYRIMIDINYL)-3,4-DIHYDRO-6-HYDROXY-2,5,7,8-TETRAMETHYL-, (S)-

Systematic Name

English

2H-1-BENZOPYRAN-2-CARBOXAMIDE, N-(6-AMINO-1,2,3,4-TETRAHYDRO-3-METHYL-2,4-DIOXO-1-PHENYL-5-PYRIMIDINYL)-3,4-DIHYDRO-6-HYDROXY-2,5,7,8-TETRAMETHYL-, (2S)-

Systematic Name

English

(-)-CX-659S

Common Name

English

Code System Code Type Description

PUBCHEM

9869053

Created by admin on Sat Dec 16 09:34:34 GMT 2023 , Edited by admin on Sat Dec 16 09:34:34 GMT 2023

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CAS

204980-81-4

Created by admin on Sat Dec 16 09:34:34 GMT 2023 , Edited by admin on Sat Dec 16 09:34:34 GMT 2023

PRIMARY

FDA UNII

YG2F04AVMQ

Created by admin on Sat Dec 16 09:34:34 GMT 2023 , Edited by admin on Sat Dec 16 09:34:34 GMT 2023

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Related Record Type Details


					YG2F04AVMQ

CX-659S

ACTIVE MOIETY