U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:57:26 GMT 2023
Edited
by admin
on Sat Dec 16 15:57:26 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG2
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
YB18NF020M
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
SATRALIZUMAB
INN  
USAN   INN  
Official Name English
SA237
Code English
SATRALIZUMAB [USAN]
Common Name English
SATRALIZUMAB [MI]
Common Name English
HUMANISED ANTI-IL-6 RECEPTOR MONOCLONAL ANTIBODY
Common Name English
SA-237
Code English
IMMUNOGLOBULIN G2-KAPPA, ANTI-(HUMAN INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA (IL-6RA, MEMBRANE GLYCOPROTEIN 80, CD126 ANTIGEN)) HUMANIZED MONOCLONAL ANTIBODY: .GAMMA.2 HEAVY CHAIN (1-443) (HUMANIZED VH (HOMO SAPIENS IGHV4-59*01 (76%) (IGHD)-IGHJ4*01 (92%))
Systematic Name English
SAPELIZUMAB
WHO-DD  
Official Name English
SATRALIZUMAB [JAN]
Common Name English
satralizumab [INN]
Common Name English
IMMUNOGLOBULIN G2, ANTI-(HUMAN INTERLEUKIN 6 RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL SA237 HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL SA237 LIGHT CHAIN, DIMER
Common Name English
Satralizumab [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
EU-Orphan Drug EU/3/16/1680
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
NCI_THESAURUS C574
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
Code System Code Type Description
DAILYMED
YB18NF020M
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
PRIMARY
RXCUI
2391541
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
PRIMARY
SMS_ID
100000181406
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
PRIMARY
USAN
DE-75
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
PRIMARY
FDA UNII
YB18NF020M
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
PRIMARY
INN
10065
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
PRIMARY
NCI_THESAURUS
C152307
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
PRIMARY
CAS
1535963-91-7
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
PRIMARY
MERCK INDEX
m12223
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
PRIMARY
WIKIPEDIA
Satralizumab
Created by admin on Sat Dec 16 15:57:26 GMT 2023 , Edited by admin on Sat Dec 16 15:57:26 GMT 2023
PRIMARY
From To
1_22 1_96
1_146 1_202
1_259 1_319
1_365 1_423
2_22 2_96
2_146 2_202
2_259 2_319
2_365 2_423
1_222 3_214
2_222 4_214
1_225 2_225
1_228 2_228
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_295
N 2_295
Related Record Type Details
TARGET -> INHIBITOR
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:SEQUENCE(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL